Senior Engineer; Downstream Process Development and Manufacturing

Position: Senior Engineer (Downstream Process Development and Manufacturing)
Company Information You Matter to Cambrex. Cambrex is a leading global contract development and manufacturing organization (CDMO) that provides drug substance development and manufacturing across the entire drug lifecycle, as well as comprehensive analytical and IND enabling services. With over 40 years of experience and a team of 2,000 experts servicing global clients from North America and Europe, Cambrex offers a range of specialized drug substance technologies and capabilities, including continuous flow, controlled substances, liquid-phase peptide synthesis, solid-state science, material characterization, and highly potent APIs.

Your Work Matters. At Cambrex, we strive to build a culture where all colleagues have the opportunity to: engage in work that matters to our customers and the patients they serve learn new skills and enjoy new experiences in an engaging and safe environment strengthen connections with coworkers and the community We're committed to attracting and nurturing a passionate team of valued professionals in our fast-paced and growing company.

We offer a competitive benefits package that includes healthcare, life insurance, planning for retirement, and more! Your Future Matters. Known for our customer-focused scientific and manufacturing excellence, as well as our strong commitment to quality and safety, we offer a range of career and growth opportunities across our global network of locations. Together with our customers, we aim to improve the quality of life for patients around the world.

Start a career where You Matter by applying today! Job Overview Snapdragon Chemistry, a Cambrex Company, is a leader in chemical process development with expertise in continuous flow and process intensification technologies. Our company is catalyzing the transformation of research, development, and manufacturing across the pharmaceutical and fine chemical industries where organic chemistry underpins product development. We rely on our most valuable resource - our people - to maintain a leadership position in this market.

As part of our dynamic team, you will have the opportunity to collaborate with world-class leaders in flow chemistry and product development while also cultivating and furthering your career. At Snapdragon Chemistry, we strive to create an environment of innovation and excellence where mutual respect and teamwork underpin our culture. We are currently seeking exceptional candidates for Senior Engineer, downstream process development and manufacturing position at its Waltham, MA site.

A successful candidate will be joining a group of innovative and entrepreneurial scientists, with broad deliverables including the development of reactor systems and purifications for batch and continuous flow processes, delivery of high quality, complex chemical matters to our clients, and transferring process technology to clients at their facility. We are looking for candidates who have a passion for working in a fast-paced, dynamic environment.

The ideal candidate will have a degree in chemical engineering with experience and a passion for developing new process technology. The candidate should enjoy building equipment and carrying out experiments in a laboratory environment and scaling them up for engineering batch and cGMP manufacturing. The candidate should be well versed in separation and purification techniques, such as chromatography, filtration, TFF and lyophilization or freezer drying.

Experience with continuous chromatography is preferred but not required. Candidates must possess strong written and oral communication skills. Responsibilities Duties and Responsibilities Develop and optimize multi-dimensional purification strategies (RP-HPLC, IEX, TFF) using mechanistic modeling and first-principles knowledge Lead the development and optimize freeze-drying cycles by determining critical process parameters (CPPs) to achieve target residual moisture. Act as the Subject Matter Expert (SME) in purification, lyophilization process development, characterization, and troubleshooting.

Perform studies to scale-up from analytical scale purification to multi-kilogram production scale…