Associate Scientist, MSAT

Career Opportunities with TScan Therapeutics

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Careers At TScan Therapeutics

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TScan Therapeutics is a clinical-stage biotech seeking to revolutionize life-changing therapeutics for patients by identifying novel T cells and epitopes. We are looking for an experienced Associate Scientist to join our Manufacturing Science and Technology (MSAT) team, supporting TScan’s cell therapy manufacturing process development and GMP production of clinical cell therapy candidates. The ideal candidate should have relevant experience in cell therapy process development, technology transfer to GMP manufacturing and GMP principles related to cell therapy, and enjoy fast-paced, collaborative and vibrant startup culture.

A team player with a sense of urgency will thrive in this role.

• Designs and executes laboratory-based studies to support new process/ equipment/materials implementation into GMP manufacturing to improve manufacturability and reduce COGs.
• Contributes to technology transfer and process implementation.
• Develops and contributes to technical documents, including tech transfer protocol and report, GxP protocol and study report, SOPs, and master batch records.
• Monitor process performance and assist with trend analysis to identify opportunities for optimization and continuous improvement.
• Work collaboratively with Manufacturing, Quality Assurance, Quality Control, Supply Chain, and Process Development teams.
• Travel to external manufacturing partners to serve as person-in-plant, train manufacturing operators, and oversee process execution
• Practices and promotes safe work habits and adheres to TScan’s safety procedures and guidelines.

• Bachelor’s or Master’s degree in Biological Sciences, Biomedical Engineering, Biotechnology, Chemical Engineering, or a related field with 5–8 years of experience in biopharmaceutical manufacturing, process development, or MSAT support.
• Industry experience in cell therapy GMP manufacturing, process technical transfer, change management, and GMP quality systems is required.
• Knowledge and experience with practices and equipment to run cell therapy manufacturing processes in a GMP environment, including Rotea, G-Rex, Prodigy, LOVO, etc.
• This position may require 10-30% travel to CDMO in the US.
• Working knowledge and experience with genetic material delivery by electroporation is preferred.
• Working knowledge of GMP regulations and ICH/quality guidelines related to cell therapy manufacturing.
• Excellent communication and interpersonal skills to coordinate complex technical/scientific CMC projects cross-functionally.
• Excellent ability to handle multiple tasks while meeting timelines and adapting to changing priorities.
• Highly organized with close attention to detail.

$108,000 - $120,000

TScan Therapeutics’ pay ranges are established based on external market data from third‑party compensation surveys and our internal benchmarking. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Individual compensation within this range is commensurate with a candidate’s specific qualifications, including education, overall experience, relevant experience, and specific skills.

We strive to ensure that compensation is competitive, equitable, and aligned with the value each TScanner brings to the role.

TScan is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. TScan provides reasonable accommodations to qualified applicants and employees with disabilities.

To begin an interactive dialogue with TScan regarding a reasonable accommodation in connection with the hiring process and/or to perform the responsibilities of the position for which the applicant has applied, please contact the recruiter.