Director, People Operations

Our commitment to people with neuromuscular diseases

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations.

At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at , and follow us onX ,Linked In and Facebook .

The Director, People Operations is responsible for leading and executing Dyne’s HR Operations strategy, operating model, and roadmap across onboarding , HRIS administration, benefits coordination, HR compliance, vendor management, reporting and analytics, service delivery, and process optimization. This hands‑on role balances day-to-day HR operational execution with strategic ownership of scalable, data informed processes that improve efficiency, consistency, compliance, and the employee experience.

The Director , People Operations serves as a trusted partner to HR leadership, managers, employees, and cross‑functional stakeholders, ensuring that peopl e processes are practical, data-informed, compliant, and aligned with Dyne’s culture , values, and business priorities. This role will provide leadership across HR systems, employee lifecycle operations, onboarding, vendor governance, service delivery, analytics, and process transformation, helping to build a scalable P eople O perations function that supports Dyne’s continued growth and commercialization readiness.

This role is office- based in Waltham, MA.

• Lead the strategy and operating priorities for core People operations while directly conducting and supporting day-to-day activities across onboarding, HRIS administration, benefits coordination, employee life-cycle administration, reporting, vendor management, and compliance
• Lead the operational execution of annual and recurring HR programs, including compensation cycles, performance management, talent processes, employee lifecycle events, and related communications, timelines, tools, data preparation, reporting, and issue resolution in close partnership with HR Business Partners, Total Rewards, Talent Acquisition, Finance, Legal, and HR leadership
• Execute and manage day-to-day HR operations tasks as needed, including responding to employee and manager inquiries, resolving operational issues, ensuring accurate employee data, coordinating process steps, and ensuring timely completion of recurring HR operational activities including benefit audits, employee onboarding , and compliance‑driven reporting
• Lead and support the People Operations Team with New Employee Orientation, including attending and presenting at orientation sessions, providing relevant onboarding details to new hires and fielding questions from new hires, managers, and hiring teams
• Provide strategic ownership and governance for ADP Workforce Now and related HR technology platforms configuration , ensuring data integrity, scalable workflows, effective integrations, automation, and reliable reporting
• Lead the strategy, design, governance , and continuous improvement of Dyne’s onboarding experience, ensuring programs , systems, and manager enablement support a consistent, engaging, and values‑aligned new hire experience
• Serve as a functional expert for complex HR operational inquiries, providing practical guidance to employees, managers, HR partners , and leaders on policies, processes, systems , and service delivery expectations
• Develop , govern, and continuously improve scalable HR service delivery processes, including inquiry intake, knowledge resources, service expectations, issue resolution, and operational metrics that improve responsiveness, consistency, accountability, and employee experience
• Serve as a key partner and stakeholder in developing Dyne’s HR IT & Technology Roadmap ,…