Director,US Commercial Enablement Job Waltham area,Massachusetts USA,IT/Tech

Company Overview

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease.

At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at , and follow us on X, Linked In and Facebook.

Company Overview

Role Summary

The Director, US Commercial Enablement drives strategic commercial enablement initiatives and builds foundational tools, processes, and capabilities to support business growth and launch readiness. The Director establishes and optimizes field enablement infrastructure, including incentive compensation, CRM platforms, and business intelligence tools, while ensuring alignment across cross-functional stakeholders. This role enhances field effectiveness, builds scalable processes, and promotes operational excellence with a patient-first mindset.

This position is based in Waltham, MA

Primary Responsibilities Include

Incentive Compensation and Performance Programs

Leads planning, design, and administration of incentive compensation and bonus programs across commercial, medical, and patient services teams
Develops plan design models, manages payouts, and delivers monthly and quarterly reporting
Maintains plan documentation, tracking systems, and performance monitoring processes
Conducts regular performance reviews with stakeholders to optimize program effectiveness
Partners with field teams to build account planning tools
Leads recognition programs, including Circle of Excellence and associated planning

Commercial Systems, Tools, and Analytics

Serves as commercial business owner for CRM platforms (e.g., Veeva), translating field needs into system enhancements
Partners with IT and stakeholders to implement and optimize CRM and data solutions
Owns business intelligence reporting tools and ensures data accuracy through quality control processes
Supports reporting platforms across market access and patient services
Optimizes field enablement tools and materials to improve productivity and effectiveness

Field Operations and Infrastructure

Designs and implements fleet program aligned with business needs and industry benchmarks
Maintains and updates fleet policies in collaboration with Compliance, HR, Finance, and Field Leadership
Builds scalable processes to support field teams and commercial operations

Cross-Functional Planning and Execution

Leads coordination of national, regional, and headquarters meetings in partnership with Marketing and Commercial teams
Drives cross-functional planning across Sales, Marketing, Market Access, Advanced Analytics, Patient Services, Finance, and IT
Ensures alignment and readiness to support commercial launch and execution
Strengthens collaboration and communication across teams

Education And Skills Requirements

Bachelor’s degree; advanced degree preferred
12+ years of experience in biotech, pharmaceutical, or life sciences industry, including field sales, sales leadership, field operations, or consulting experience supporting commercial organizations
Demonstrated experience supporting or leading launch readiness, ideally in rare disease, neuromuscular, neurodegenerative, or neurodevelopmental…