Director​/Senior Director, IT Operations and Governance - Crescent Biopharma

Crescent Biopharma's vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients. The Company's clinical-stage pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. By leveraging multiple modalities and established targets, Crescent aims to rapidly advance potentially transformative therapies as single agents and as part of combination regimens to treat a range of solid tumors.

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We are seeking a Director/Senior Director to serve as the operational leader of the Information Technology function and be responsible for executing the company's technology strategy, roadmap, and governance framework. Reporting to the VP, Information Technology, you are responsible for translating the company's technology strategy into executable plans and ensuring successful delivery through internal resources, managed service providers, consultants, and business stakeholders.

You will oversee technology operations, project execution, governance, compliance, and vendor management while helping build scalable, audit-ready processes that support Crescent's growth and clinical development objectives. You will also serve as a key partner to business leaders across the organization and play an important role in advancing operational excellence, and cybersecurity maturity.

• Translate IT strategy and roadmap into actionable projects, workplans, and operational initiatives.
• Provide leadership and direction to internal IT personnel, contractors, and managed service providers.
• Oversee day-to-day IT operations and service delivery.
• Partner with business leaders across Clinical Development, Regulatory, Quality, Finance, Legal, HR, and other functions to prioritize technology initiatives and ensure successful delivery of business outcomes.
• Direct execution of technology initiatives across infrastructure, cybersecurity, collaboration platforms, business applications, and GxP systems.
• Manage project portfolios and ensure timely delivery of priorities, milestones, risks, and dependencies.
• Manage relationships with managed service providers, consultants, software vendors, and implementation partners.
• Coordinate internal stakeholders and external resources to ensure technology initiatives remain on schedule and within scope.
• Lead development, maintenance, and implementation of IT policies, standards, SOPs, and operational procedures.
• Support cybersecurity, privacy, and regulatory compliance initiatives including NIST CSF, GxP requirements, data protection regulations, and audit readiness activities.
• Maintain governance processes, documentation, and evidence required for inspections, audits, and due diligence reviews.