Senior Manager, Logistics

Company Overview
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations.

At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at , and follow us on X, Linked In and Facebook.

Company Overview
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations.

At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at , and follow us on X, Linked In and Facebook.
Role Summary
The Senior Manager plays a critical role in managing end-to-end logistics operations for both clinical and commercial supply. The role will be responsible for the coordination and oversight of cold chain material movements between Contract Manufacturing Organizations (CMOs), warehouses, and distribution partners. The Senior Manager partners closely with Supply Chain, Quality, Manufacturing, Finance, Commercial, and external partners and stakeholders to ensure seamless logistics operations, supply continuity, compliant flow of materials, as well as clinical study and commercial launch readiness.

This is a hands-on operational role with strategic elements focused on day-to-day warehouse and courier management, process improvements, development and maintenance of Standard Operation Procedures (SOP), and readiness for product commercialization.
This role is based in Waltham, MA and requires on-site presence.

Logistics Operations
Coordinate and oversee domestic and international cold chain shipments between Contract Manufacturing Organizations (CMO), warehouses, Third-Party Logistics Providers (3PL) and other supply chain nodes.

Serve as the Logistics lead for network re-supply, working closely with internal stakeholders (e.g. Supply Planning, Quality, Manufacturing) and external partners (e.g. couriers, CMOs, customs brokers, warehouses, 3PLs).

Ensure timely and compliant execution of shipments, including documentation preparation and review, courier booking, shipment tracking, import/export activities, post-shipment follow-up and closure.

Troubleshoot logistics issues and implement corrective actions as needed.

Ensure all logistics activities are conducted in compliance with GMP, GDP, and international trade regulations and maintain accurate shipment documentation.

Support the set up of the 3PL for commercial launches.

Collaborate with cross-functional teams to establish processes and capabilities to support ongoing and future commercial operations.

Develop, implement and maintain the necessary SOPs and Work Instructions.

Develop and maintain strong, collaborative relationships with internal teams and external stakeholders and partners.

Monitor courier, warehouse and 3PL performance and drive improvements.

Act as logistics liaison in cross-functional and partner meetings to ensure alignment and proactive communication.

• Bachelor’s degree in Supply Chain Management, Logistics, Life Sciences, or a related field. Advanced degree or certification (e.g., APICS, IATA, SCPro) is a plus.
• Minimum of 6 years of experience in supply chain, logistics, or trade compliance within biotechnology, pharmaceuticals, healthcare, or another regulated industry.
• Stron…