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Strategic Program Operations Lead

Job in Waltham, Middlesex County, Massachusetts, 02254, USA
Listing for: Upstream Bio
Full Time position
Listed on 2026-08-11
Job specializations:
  • Management
    Operations Management, Regulatory Compliance Specialist
Salary/Wage Range or Industry Benchmark: 174000 - 213000 USD Yearly USD 174000.00 213000.00 YEAR
Job Description & How to Apply Below

Upstream Bio is seeking a Senior Manager, Program Operations to act as the operational backbone for CDT-wide planning and cross-study reporting in Waltham, MA. You will own integrated timelines, dashboards, and risk registers, translating SMT inputs into CDT and Asset Team updates.

In this role, you’ll coordinate with CMC, Regulatory, and Clinical Operations partners, ensure timely escalation of issues, and drive governance materials for leadership reviews while maintaining lean processes and

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