Research Associate - RNA Synthesis Platform Development

** Job title** :  _Research Associate - RNA Synthesis Platform Development_

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Location:

Waltham, MA_

** About the Job*
* Are you passionate about advancing RNA therapeutics and cutting-edge biotechnology? We're seeking a talented Research Associate - RNA Synthesis Platform Development to join our dynamic team in Waltham, where innovation meets impact in the rapidly evolving world of mRNA technology.

Join the engine of Sanofi's mission - where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

** About Sanofi:*
* We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system - and innovative pipeline - enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

** Basic Qualifications*
* + Bachelor's degree in Biochemistry or related fields.

+ Minimum 2 years of hands-on experience in an industrial laboratory setting.

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* Main responsibilities:

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* As a Research Associate in our RNA synthesis group, you'll be at the forefront of developing next-generation therapeutic platforms. Your work will directly contribute to breakthrough treatments that could transform patients' lives worldwide.

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** Drive Platform

Innovation:
** Support individual program development through the application of cutting-edge platform synthesis technologies.

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** Technology Development:
** Evaluate and develop new technologies for improving current platform processes, pushing the boundaries of what's possible in RNA synthesis.

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** Automated Systems Management:
** Operate and optimize Hamilton Vantage automated systems and liquid handling platforms using Venus software.

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** Enzymatic Process Optimization:
** Design and execute enzymatic reactions with a focus on in vitro transcription and enzyme kinetics

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** Quality Control & Analysis:
** Perform comprehensive nucleic acid purification and characterization using advanced analytical techniques.

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** Data-Driven Decision Making:
** Design experiments and conduct quantitative data analysis to drive scientific conclusions.

** Additional Qualifications*
* Technical Expertise:

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** Biochemistry Foundation:
** Strong background in enzymatic reactions and catalysis, with particular emphasis on in vitro transcription (IVT) reactions and enzyme kinetics.

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** RNA Biochemistry:
** Demonstrated expertise in RNA synthesis, protein and nucleic acid biochemistry, and enzymatic process development (preferably in mRNA manufacturing).

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** Laboratory Automation:
** Experience with Hamilton Vantage automated systems and Venus software for liquid handling methods

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** Analytical Techniques:
** Proficiency in RNA purification and characterization assays including Ethanol precipitation, Spectrophotometry, Capillary electrophoresis, ELISA and qPCR methodologies.

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** Scientific Rigor:
** Strong experimental design skills and quantitative data analysis capabilities.

Essential

Skills:

+ Fluency in English (written and verbal).

+ Detail-oriented with excellent organizational skills.

+ Collaborative mindset with strong communication abilities.

+ Adaptability in a fast-paced, innovative environment.

** Why Choose Us*
* + Bring the miracles of science to life alongside a supportive, future-focused team.

+ Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.

+ Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

+ Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

+ Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

+ Help improve the lives of millions of people globally by making drug development quicker and more effective.

+ Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status;

domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic…