Research Associate - RNA Synthesis Platform Development

Job title:

Research Associate - RNA Synthesis Platform Development

* Location:

Waltham, MA

About the Job

Are you passionate about advancing RNA therapeutics and cutting-edge biotechnology? We're seeking a talented Research Associate - RNA Synthesis Platform Development to join our dynamic team in Waltham, where innovation meets impact in the rapidly evolving world of mRNA technology.

Join the engine of Sanofi's mission - where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi:

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system - and innovative pipeline - enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Basic Qualifications

* Bachelor's degree in Biochemistry or related fields.

* Minimum 2 years of hands-on experience in an industrial laboratory setting.

Main responsibilities:

As a Research Associate in our RNA synthesis group, you'll be at the forefront of developing next-generation therapeutic platforms. Your work will directly contribute to breakthrough treatments that could transform patients' lives worldwide.

* Drive Platform

Innovation: Support individual program development through the application of cutting-edge platform synthesis technologies.

* Technology Development:
Evaluate and develop new technologies for improving current platform processes, pushing the boundaries of what's possible in RNA synthesis.

* Automated Systems Management:
Operate and optimize Hamilton Vantage automated systems and liquid handling platforms using Venus software.

* Enzymatic Process Optimization:
Design and execute enzymatic reactions with a focus on in vitro transcription and enzyme kinetics

* Quality Control & Analysis:
Perform comprehensive nucleic acid purification and characterization using advanced analytical techniques.

* Data-Driven Decision Making:
Design experiments and conduct quantitative data analysis to drive scientific conclusions.

Additional Qualifications

Technical Expertise:

* Biochemistry Foundation:
Strong background in enzymatic reactions and catalysis, with particular emphasis on in vitro transcription (IVT) reactions and enzyme kinetics.

* RNA Biochemistry:
Demonstrated expertise in RNA synthesis, protein and nucleic acid biochemistry, and enzymatic process development (preferably in mRNA manufacturing).

* Laboratory Automation:

Experience with Hamilton Vantage automated systems and Venus software for liquid handling methods

* Analytical Techniques:
Proficiency in RNA purification and characterization assays including Ethanol precipitation, Spectrophotometry, Capillary electrophoresis, ELISA and qPCR methodologies.

* Scientific Rigor:
Strong experimental design skills and quantitative data analysis capabilities.

Essential

Skills:

* Fluency in English (written and verbal).

* Detail-oriented with excellent organizational skills.

* Collaborative mindset with strong communication abilities.

* Adaptability in a fast-paced, innovative environment.

Why Choose Us

* Bring the miracles of science to life alongside a supportive, future-focused team.

* Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.

* Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

* Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

* Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

* Help improve the lives of millions of people globally by making drug development quicker and more effective.

* Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital…