Research Associate - RNA Synthesis Platform Development

Job title
:
Research Associate - RNA Synthesis Platform Development

Location:

Waltham, MA

Are you passionate about advancing RNA therapeutics and cutting‑edge biotechnology? We’re seeking a talented Research Associate - RNA Synthesis Platform Development to join our dynamic team in Waltham, where innovation meets impact in the rapidly evolving world of mRNA technology.

• Bachelor’s degree in Biochemistry or related fields.
• Minimum 2 years of hands‑on experience in an industrial laboratory setting.

• Drive Platform Innovation:
  Support individual program development through the application of cutting‑edge platform synthesis technologies.
• Technology Development:
  Evaluate and develop new technologies for improving current platform processes, pushing the boundaries of what’s possible in RNA synthesis.
• Automated Systems Management:
  Operate and optimize Hamilton Vantage automated systems and liquid handling platforms using Venus software.
• Enzymatic Process Optimization:
  Design and execute enzymatic reactions with a focus on in vitro transcription and enzyme kinetics.
• Quality Control & Analysis:
  Perform comprehensive nucleic acid purification and characterization using advanced analytical techniques.
• Data‑Driven Decision Making:
  Design experiments and conduct quantitative data analysis to drive scientific conclusions.

• Biochemistry Foundation:
  Strong background in enzymatic reactions and catalysis, with particular emphasis on in‑vitro transcription (IVT) reactions and enzyme kinetics.
• RNA Biochemistry:
  Demonstrated expertise in RNA synthesis, protein and nucleic acid biochemistry, and enzymatic process development (preferably in mRNA manufacturing).
• Laboratory Automation:
  Experience with Hamilton Vantage automated systems and Venus software for liquid‑handling methods.
• Analytical Techniques:
  Proficiency in RNA purification and characterization assays including ethanol precipitation, spectrophotometry, capillary electrophoresis, ELISA, and qPCR methodologies.
• Scientific Rigor:
  Strong experimental design skills and quantitative data analysis capabilities.

• Fluency in English (written and verbal).
• Detail‑oriented with excellent organizational skills.
• Collaborative mindset with strong communication abilities.
• Adaptability in a fast‑paced, innovative environment.

• Supportive, future‑focused team.
• Opportunities for career growth and promotion.
• Competitive compensation package.
• Comprehensive health and wellbeing benefits, including high‑quality healthcare and a gender‑neutral parental leave program.
• Involvement in pioneering biopharma projects with patient‑centric design.
• Use of AI, data, and digital platforms to accelerate drug discovery.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and affirmative action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital status, domestic partnership or civil union status, sex, gender, gender identity or expression, sexual orientation, disability, veteran or military status, or any other characteristic protected by law.