Research Associate - RNA Synthesis Platform Development

Job title
:
Research Associate - RNA Synthesis Platform Development

Location:

Waltham, MA

Are you passionate about advancing RNA therapeutics and cutting-edge biotechnology? We're seeking a talented Research Associate - RNA Synthesis Platform Development to join our dynamic team in Waltham, where innovation meets impact in the rapidly evolving world of mRNA technology.

Join the engine of Sanofi’s mission—where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system—and innovative pipeline—enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

• Bachelor's degree in Biochemistry or related fields.
• Minimum 2 years of hands‑on experience in an industrial laboratory setting.

As a Research Associate in our RNA synthesis group, you'll be at the forefront of developing next‑generation therapeutic platforms. Your work will directly contribute to breakthrough treatments that could transform patients’ lives worldwide.

• Drive Platform Innovation:
  Support individual program development through the application of cutting‑edge platform synthesis technologies.
• Technology Development:
  Evaluate and develop new technologies for improving current platform processes, pushing the boundaries of what's possible in RNA synthesis.
• Automated Systems Management:
  Operate and optimize Hamilton Vantage automated systems and liquid handling platforms using Venus software.
• Enzymatic Process Optimization:
  Design and execute enzymatic reactions with a focus on in vitro transcription and enzyme kinetics.
• Quality Control & Analysis:
  Perform comprehensive nucleic acid purification and characterization using advanced analytical techniques.
• Data‑Driven Decision Making:
  Design experiments and conduct quantitative data analysis to drive scientific conclusions.

Technical Expertise:

• Biochemistry Foundation:
  Strong background in enzymatic reactions and catalysis, with particular emphasis on in vitro transcription (IVT) reactions and enzyme kinetics.
• RNA Biochemistry:
  Demonstrated expertise in RNA synthesis, protein and nucleic acid biochemistry, and enzymatic process development (preferably in mRNA manufacturing).
• Laboratory Automation:
  Experience with Hamilton Vantage automated systems and Venus software for liquid handling methods.
• Analytical Techniques:
  Proficiency in RNA purification and characterization assays including ethanol precipitation, spectrophotometry, capillary electrophoresis, ELISA, and qPCR methodologies.
• Scientific Rigor:
  Strong experimental design skills and quantitative data analysis capabilities.

• Fluency in English (written and verbal).
• Detail‑oriented with excellent organizational skills.
• Collaborative mindset with strong communication abilities.
• Adaptability in a fast‑paced, innovative environment.

• Bring the miracles of science to life alongside a supportive, future‑focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high‑quality healthcare, prevention and wellness programs and at least 14 weeks’ gender‑neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real‑world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting‑edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc.…