Research Associate - RNA Synthesis Platform Development

Research Associate - RNA Synthesis Platform Development

Location:

Waltham, MA

Are you passionate about advancing RNA therapeutics and cutting-edge biotechnology? We're seeking a talented Research Associate - RNA Synthesis Platform Development to join our dynamic team in Waltham, where innovation meets impact in the rapidly evolving world of mRNA technology.

Join the engine of Sanofi's mission — where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

Basic Qualifications

• Bachelor's degree in Biochemistry, Molecular Biology, Chemical Engineering, or related field.
• 1+ years of hands-on experience in an industrial laboratory setting.

Additional Qualifications

• Biochemistry Foundation:
  Strong background in enzymatic reactions and catalysis, with particular emphasis on in vitro transcription (IVT) reactions and enzyme kinetics.
• RNA Biochemistry:
  Demonstrated expertise in RNA synthesis, protein and nucleic acid biochemistry, and enzymatic process development (preferably in mRNA manufacturing).
• Laboratory Automation:
  Experience with Hamilton Vantage automated systems and Venus software for liquid handling methods
• Analytical Techniques:
  Proficiency in RNA purification and characterization assays including Ethanol precipitation, Spectrophotometry, Capillary electrophoresis, ELISA and qPCR methodologies.
• Scientific Rigor:
  Strong experimental design skills and quantitative data analysis capabilities.

Language &

Soft Skills:

• Fluency in English (written and verbal).
• Detail-oriented with excellent organizational skills.
• Collaborative mindset with strong communication abilities.
• Adaptability in a fast-paced, innovative environment.

Main Responsibilities:

• Drive Platform Innovation:
  Support individual program development through the application of cutting-edge platform synthesis technologies.
• Technology Development:
  Evaluate and develop new technologies for improving current platform processes, pushing the boundaries of what's possible in RNA synthesis.
• Automated Systems Management:
  Operate and optimize Hamilton Vantage automated systems and liquid handling platforms using Venus software.
• Enzymatic Process Optimization:
  Design and execute enzymatic reactions with a focus on in vitro transcription and enzyme kinetics
• Quality Control & Analysis:
  Perform comprehensive nucleic acid purification and characterization using advanced analytical techniques.
• Data-Driven Decision Making:
  Design experiments and conduct quantitative data analysis to drive scientific conclusions.

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status;

domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.