Senior Scientist, Research

Visterra, Inc. is seeking to hire a Senior Scientist with strong expertise in immunology and a deep understanding of immune-related diseases, along with broad experience in the discovery and development of antibody-based therapeutics.

This individual will play a key role in drug discovery programs by conceiving, developing, and implementing assays to support the discovery and validation of therapeutic antibody candidates. The successful candidate will be a collaborative team player, an effective manager, a critical thinker, and a clear communicator. The ideal candidate will have an advanced degree (Ph.D. or equivalent) in immunology, biology, biochemistry, or a related field, along with a minimum of 3 years of post-graduate research experience in a biotechnology or pharmaceutical setting.

Prior experience managing early-career research scientists is required

This is a full-time, on-site position located at Visterra’s headquarters in Waltham, M

• ies Design and execute experiments involving immunization strategies, antibody library generation, antibody engineering, and in vitro/in vivo characterization of antibody-antigen interactio
• ns.
  
  Provide scientific leadership on project-based team, advancing therapeutic programs from conception through pre-clinical studi
• es.
  
  Effectively contributes to project strategy development by demonstrating a strong understanding of target biology and aligning experimental approaches with overall program goa
• ls.
  
  Independently and critically analyze scientific results, troubleshoot methods, and conceive creative solutions and workflows to address challeng
• es.
  
  Document, analyze and interpret data for internal decision making, publications, presentations, patents and regulatory filin
• gs.
  
  Develop research plans and manage multiple workflows
• and Manage activities at contract research organizations (CRO
• s).Maintain expertise in the field by staying current to relevant literature and attending relevant conferenc

• entsA Ph.D. or equivalent advanced degree in Immunology, Biochemistry, Biology, Biotechnology, or a related field, with a minimum of three years of post-graduate research experience in the biotechnology or pharmaceutical indus
• try.
  
  Experience working with immune-related diseases, with a strong understanding of disease biology relevant to therapeutic developm
• ent.
  
  Expertise in antibody discovery, including protein engineering, expression and purification, and automation of screening and characterization workfl
• ows.
  
  Skilled in designing and executing in vitro and in vivo studies to investigate disease biology and assess efficacy, PK, PD, and mechanism of action of drug candida
• tes.
  
  Strong data analysis skills, with the ability to interpret complex experimental results and draw meaningful conclusi
• ons.
  
  Excellent scientific communication skills, both written and oral, including the ability to clearly present data and concepts in meetings, reports, and publicati
• ons.
  
  Self-motivated and capable of independent work in a laboratory setting, while also contributing effectively to collaborative team environme

• tions
  
  Experience with antibody discovery platforms, such as phage display, yeast display, and next-generation sequencing (NGS), as well as antibody binding characterization techniques such as biolayer interferometry (BLI) and surface plasmon resonance (
• SPR).Experience with flow cytometry (FACS) and a range of immunological techniques, such as ELISA, multiplex cytokine assays, and immune cell profi
• ling.
  
  Experience with high-throughput automation technologies, such as a Tecan liquid handling r
• obot.
  
  A proven track record of working in a dynamic team of scientists, early-career research assoc

mpany Visterra is a clinical stage biotechnology company committed to developing innovative antibody-based therapies for the treatment of patients with kidney, immune-mediated and other hard-to-treat diseases. Our proprietary technology platform enables the design and engineering of precision antibody-based product candidates that specifically bind to, and modulate, key disease targets. Applying this technology to disease targets that are not adequately…