Scientific Operations Manager​/Associate Scientist, Oligonucleotide Synthesis & Analytical Sciences

Role

Location:

Waltham, MA

The Company

We are Alloy Therapeutics — a biotechnology ecosystem and Product Development Organization (PDO) empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma.

At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. May the Best Drug Win.

Alloy has evolved from a startup into a global product development organization operating 11 divisions across 5 research sites in 4 countries on 3 continents. Our model
- Integrated Independence - combines centralized capabilities with entrepreneurial operating divisions. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture.

At Alloy, we have an ethos of "Mentorship-By-Apprenticeship" in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day.

We ask our people who have more flexible accommodations to appreciate their colleagues who have less flexibility. We are all one team!

We are seeking a Scientific Operations Manager / Associate Scientist to split their time approximately 50/50 between (1) managing the operational backbone of our oligonucleotide design-make-test cycle (Nucleic Acid Chemistry or NAC) and (2) hands‑on chemistry work in the laboratory, including synthesis, purification, and quality control.

The ideal candidate brings a strong operations mindset—a deep appreciation for process discipline, documentation rigor, and quality systems—paired with genuine comfort at the bench. Prior oligonucleotide experience is not required; we will train the right person on our synthesis platform and analytical methods. What matters is that you have run reactions, operated instruments, and managed the operational machinery of a research-stage chemistry or manufacturing organization.

You are equally comfortable troubleshooting a synthesis as you are building a demand plan, and you thrive on bringing structure and visibility to fast-moving research operations.

A rare opportunity to shape the operational foundation of a growing genetic medicines company from the ground up. You will have a direct impact on how our team designs, makes, and tests novel oligonucleotide therapeutics—while staying connected to the science at the bench. We will invest in training you on our nucleic acid chemistry platform so that you develop deep expertise in an exciting and rapidly expanding therapeutic modality.

We offer competitive compensation, equity participation, and the chance to build something meaningful alongside a deeply experienced team.

• Sequence Request Intake, Demand Planning, Scheduling & Queue Management
  • Own…