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Senior Medical Director, Early Clinical Development & Translational Medicine; MD

Job in Waltham, Middlesex County, Massachusetts, 02254, USA
Listing for: Scorpion Therapeutics
Full Time position
Listed on 2026-09-14
Job specializations:
  • Research/Development
  • Doctor/Physician
Salary/Wage Range or Industry Benchmark: 260000 - 380000 USD Yearly USD 260000.00 380000.00 YEAR
Job Description & How to Apply Below
Position: Senior Medical Director, Early Clinical Development & Translational Medicine (MD)

Role:
Senior Medical Director, Translational Medicine & Early Clinical Development, leading early phase and mechanistic studies in Madrigal's metabolic liver and cardiometabolic portfolio.

Responsibilities: serve as medical lead for first-in-human, proof-of-concept, and indication-expansion trials; design protocols, oversee safety and data interpretation; define translational and biomarker strategies; chair or co-chair early asset teams; collaborate across research, clinical, biomarker, and regulatory functions; represent the company externally at scientific forums; mentor junior staff and refine operating models.

Qualifications:

MD with >15 years industry experience in clinical development, with a focus on translational medicine, biomarkers, and metabolic liver or cardiometabolic diseases preferred; strong leadership, communication, and cross-functional influencing skills; regulatory agency interaction experience is a plus.

High Value: early phase (FIH, PoC), mechanistic studies, metabolic liver/cardiometabolic indications, biomarker integration, global collaboration, hybrid work setup in PA or MA. Travel requirements are not specified but may include external engagement and conferences.

Position Requirements
10+ Years work experience
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