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Principal Software Engineer

Job in Waltham, Middlesex County, Massachusetts, 02254, USA
Listing for: Talener
Full Time position
Listed on 2026-02-16
Job specializations:
  • Software Development
    Software Engineer, AI Engineer
Salary/Wage Range or Industry Benchmark: 80000 - 100000 USD Yearly USD 80000.00 100000.00 YEAR
Job Description & How to Apply Below

Position Overview

  • Job Title: Principal Software Engineer
  • Company: Publicly traded Bio Pharma/Life Sciences Services
  • Location: Remote (US)
About the Role

You will join the team building a unified cloud-native platform that serves over 1 million scientists worldwide. Your code will directly support the "Design-Make-Test-Decide" lifecycle, helping pharmaceutical and biotech companies bring life‑saving therapies to market faster.

The Technology Stack
  • Core Backend: Python (Some legacy Java)
  • Cloud Infrastructure: AWS (S3, Lambda, EC2, RDS)
  • Containerization: Docker, Kubernetes
  • Frontend: React / Type Script (for full‑stack context)
Key Responsibilities
  • Technical Architecture: Design and own architecture for critical components of the Data Factory and Lab Notebook Suite, ensuring high availability and scalability for processing petabytes of scientific data.
  • Hands‑on Development: Write high‑quality, testable, and secure Python for complex data transformation pipelines and RESTful microservices.
  • Technical Leadership: Guide and mentor senior and mid‑level engineers on best practices, code reviews, and design patterns without necessarily having direct management reports.
  • Innovation: Prototype and integrate emerging technologies (including AI/ML workflows) to enhance the capability of scientists to analyze chemical and biological data.
  • Cross‑Functional

    Collaboration:

    Partner with Product Management and UX to translate complex scientific requirements into robust technical specifications.
Qualifications
  • 5‑10+ years of Software Engineering experience
  • 5‑10+ years of Technical Lead experience, driving AI business initiatives
  • 5‑10+ years of designing and implementing AI infrastructure, including building applications powered by LLMs
  • 5‑10+ years of programming skills in Python and Java
  • Bonus: Experience with Cheminformatics, Bioinformatics, or laboratory workflows is a significant plus.
  • Bonus: Bachelor or Master in Computer Science or related field.
Benefits & Culture & Compensation
  • Health: Comprehensive Medical, Dental, and Vision options.
  • Family: Generous parental leave.
  • Financial: Base Salary in the 190-220k Range, with 10% Target Bonus, 401k with 4% company match and Employee Stock Purchase Plan (ESPP).

For immediate consideration, please contact Matt Morton –

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