Molecule Steward; Senior Director), Long-Acting Injectables

Job description

Site Name: UK - Hertfordshire - Ware, Aranda, Belgium-Wavre, France - Evreux, GSK HQ, USA - Pennsylvania - King of Prussia
Posted Date: Feb 23 2026

We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance. Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations;

it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply. We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.

The Molecule Steward (Sr Director) is the single point of end to end technical accountability for a portfolio of long acting injectable products, including DS, DP, inspection, assembly, packing and related support activities, providing strategic Technical leadership to ensure successful new product introduction, and improvements across the lifecycle (e.g. quality, robustness and productivity). The Molecule Steward (Sr Director) is aligned to a new asset at Commit to Commercial Design with responsibility for representing MSAT in the development of the Product Control Strategy.

When the product transfers to GSC accountability, the Molecule Steward co-ordinates Drug Substance, Drug Product, Analytical Strategy and Device Lead to maintain the Product Control Strategy and ensure the product is maintained in the desired state of control through product lifecycle. The Molecule Steward (Sr Director) is responsible for developing and delivering the technical elements of the GSC strategy for long-acting injectable products with the GSC Strategic Lead.

The Molecule Steward (Sr Director) will be the recognised expert in long-acting injectable products and in addition to strategic technical leadership, the role will be expected to provide deep technical expertise where required to ensure highest levels of quality and robustness.

• Responsible for defining and owning the technical strategy through a product’s lifecycle including product transfers R&D to GSK sites/ External manufacturing sites & Site to Site (both GSK sites and external manufacturing sites), Product Performance Qualification and Ongoing Continuous Process Verification, leading Product Technical Lifecycle Team (PTLT) and yearly Manufacturing Robustness Review Board meetings (MRRB) to ensure risks are identified, escalated, mitigated and resolved ensuring alignment and consistency across supply nodes.
• Accountable for developing and delivering the Technical Lifecycle Plan (TLCP) including major geographical expansion requiring additional CMC activities on top of wave 1, new technologies and second generation programs impacting the manufacturing process, analytical process, pack, device, and associated specifications.
• Ensures that product history and knowledge from development through the product’s lifecycle is maintained and aligns with knowledge management standards for the product or dose form within the GSC network. Molecule steward is contributing as key inputter for process history file (PHF) reviewer and approver (if applicable).
• Providing technical leadership and subject matter expertise where required for multi-site investigations and/or critical deviations, troubleshooting, and major change programmes across supply nodes.
• Stays current and maintains solid knowledge and understanding of complex scientific subject matter as well as evolving regulatory policies and guidelines and industry best practices.
• Responsible for co-ordinating the technical review of regulatory submissions and responses to technical…