Principal Software Engineer

Join Amgen’s mission of serving patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission to serve patients living with serious illnesses drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions.

As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team.

Lead the architecture, design, and development of modern, enterprise‑grade user interfaces that support Contracting, Pricing, and Commercial Operations business processes. Leverage React, Type Script, and contemporary frontend technologies to build intuitive, responsive, and highly interactive applications that deliver exceptional user experiences while adhering to enterprise standards for scalability, accessibility, security, and maintainability.

Drive UI innovation and digital transformation by partnering closely with business stakeholders, product teams, and engineers. Define frontend architecture, establish reusable design patterns and component frameworks, integrate AI‑powered experiences and enterprise platforms, and lead the delivery of scalable applications that improve productivity, streamline workflows, and accelerate business outcomes. Hands‑on solution design, prototyping, and implementation are required.

• Lead architecture, design, and delivery of enterprise web applications using modern frontend and backend technologies.
• Develop highly interactive user experiences using React, Type Script, Next.js, and modern frontend frameworks.
• Define and evolve enterprise frontend architecture, design systems, reusable component libraries, and UI engineering standards to ensure consistency, scalability, accessibility, and exceptional user experiences.
• Design and implement AI‑powered applications leveraging Generative AI, Large Language Models (LLMs), Retrieval‑Augmented Generation (RAG), and agentic architectures.
• Build intelligent assistants, copilots, and conversational interfaces for Contracting, Pricing, and Commercial Operations users.
• Design and implement scalable API‑driven, event‑based, and integration architectures across enterprise platforms including Salesforce, Conga CLM/CPQ, Model N, Anaplan, Databricks, Mule Soft, and other business systems.
• Partner with business stakeholders to identify opportunities for automation, AI enablement, workflow optimization, and digital transformation.
• Lead rapid prototyping and proof‑of‑concept initiatives to validate emerging technologies, AI capabilities, and business use cases.
• Lead adoption of modern Dev Ops practices including CI/CD automation, infrastructure as code, application monitoring, observability, and cloud‑native deployment strategies.
• Leverage AI‑assisted software development tools and emerging engineering platforms to accelerate prototyping, application delivery, code quality, and developer productivity.
• Establish architecture standards and engineering best practices for frontend development, AI‑powered applications, Dev Ops, security, scalability, observability, and software delivery.
• Provide technical leadership and mentorship across engineering teams, driving architecture governance, engineering excellence, Dev Ops maturity, and adoption of modern development and AI‑enabled engineering practices.

• Full‑stack application development using React.js, Next.js, Type Script, Node.js, and Python.
• Modern frontend architecture, responsive user experience…