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Executive Director of Bioinformatics

Job in Watertown, Middlesex County, Massachusetts, 02472, USA
Listing for: Soufflé Therapeutics
Full Time position
Listed on 2026-08-04
Job specializations:
  • IT/Tech
    Data Scientist, AI Engineer (Applied/Software), Machine Learning/ ML Engineer, Data Science Manager
Salary/Wage Range or Industry Benchmark: 210000 - 320000 USD Yearly USD 210000.00 320000.00 YEAR
Job Description & How to Apply Below

Souffl e9 Therapeutics | Executive Director, Bioinformatics | Job Description

Souffl e9 Therapeutics is a biotech company focusing on the cell-type specific delivery of genetic medicines. It's team of driven scientists is making a mark in delivery of oligonucleotides to extrahepatic tissues. We thrive in a purpose-building lab and office space in Watertown. Come and join us in our quest!

Position Summary

Souffl e9 is seeking an Executive Director, Bioinformatics to define and lead our multi-year bioinformatics and data science strategy across research, translational science, and clinical development. This backfill is an opportunity to bring additional breadth and AI/ML leadership as we scale, championing responsible AI/ML integration and governance while building a team that turns diverse data into decisions.

Key Responsibilities
  • Work with R&D leadership to define a multi-year bioinformatics and data science strategy across research, translational science, and clinical development
  • Lead a team that translates diverse data into insights and decisions
  • Champion responsible AI/ML integration and governance frameworks, and mechanisms to prioritize high-impact projects
  • Build a team and culture that engages and partners with stakeholders to bring new workflows, initiatives, and case studies to realization
  • Act as a collaborative, highly integrative team player across the organization
What Success Looks Like
  • In 3 months: A growth gameplan aligned for the next 2-3 years, with a plan in place for key AI/ML rollout and governance initiatives; set priorities and communicate for the next 3-6 months.
  • In 6 months:
    Successful system roll-outs, with a strong queue of high-value use cases; able to see clear early success with first roll out cases
  • In 12 months:
    Strategy set for the next stage of growth
Qualifications — Required
  • 12+ years of relevant bioinformatics/data science experience, including 4+ years in a functional leadership role
  • Strong change management and stakeholder engagement skills, with a customer-oriented working style
  • Experience defining and leading data science/bioinformatics strategy across research and clinical development functions
Qualifications — Preferred
  • Experience with multi-omic data analysis and integration, machine learning/AI methodologies, and data pipeline and dashboard development
Education
  • Ph.D. in Bioinformatics, Computational Biology, Biostatistics, Computer Science, or a related field

This is an onsite position in Watertown, MA (US) with flexibility as needed for collaboration and external engagements.

At Souffl e9 Therapeutics, we are intentional about building an equitable culture. How we treat our people is reflective of this focus. We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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