Director, Program Lead – Women's Health and Preeclampsia

Director, Program Lead - Women's Health and Preeclampsia

Boston, MA USA

Company Summary

Pro Found™ Therapeutics is a biotechnology company discovering novel proteins across the expanded human proteome to unlock transformative drug targets and first-in-class medicines. The company's proprietary Pro Foundry™ Platform integrates state-of-the-art protein detection, validation, and computational technologies to systematically identify and characterize previously unknown proteins and validate their therapeutic potential. This approach has generated a rapidly expanding portfolio of novel targets and programs advancing toward the clinic, along with strategic collaborations with leading pharmaceutical partners.

Together, these efforts support the development of breakthrough treatments across a broad range of disease areas. For more information, please visit  .

Position Summary

Pro Found Therapeutics is seeking a Director, Program Lead to lead our discovery program in Women's Health, with an initial focus on preeclampsia and hypertensive disorders of pregnancy. The Program Lead is accountable for the Project Team (PT) and for the overall technical direction, execution, and success of the program, while providing direct scientific leadership to the team executing its laboratory work.

The program is anchored by Pro Found's Gates Foundation-funded work and sits within the Cardiovascular, Metabolic, and Neuroscience therapeutic area, giving the Program Lead a funded mandate and defined collaboration goals from day one.

The successful candidate brings a strong foundation in Women's Health, vascular biology, hypertension, or a similar area of biology, as well as the scientific depth to direct and interpret mechanistic work spanning in vitro and in vivo models, and the ability to own program strategy end to end and represent it at the most senior levels of Pro Found, Flagship, and partner organizations.

The role is approximately 75% program leadership and external-facing work and 25% direct scientific leadership of the researchers executing the program's laboratory work guiding experimental design, interpreting results, and translating them into program strategy.

Key Responsibilities

• Build, sustain, and develop a motivated, high-performing PT; leverage internal and external expertise, including advisory and counseling boards; collaborate closely with groups outside the PT.
• Accountable for the PT, for the overall technical, development, and delivery success of the program, and for lean, fast execution of discovery and early development against defined milestones; able to speak to any program-related topic internally and externally.
• Lead the PT to develop and drive program strategy that achieves collaboration goals and progresses novel protein targets through the defined pipeline stages; own and update the strategy and Target Product Profile (TPP), anticipating internal and external drivers.
• Empowered to make program execution decisions; accountable for framing and recommending stage-gate and advancement options to relevant senior decision makers for continuous alignment on program vision and strategy.
• Responsible for the financial steering of long-term program budgets as assigned by senior leadership, including forecasting, prioritization of spend, and accountability for delivery against budget.
• Accountable to Pro Found management and to relevant joint oversight committees with partners for all aspects of the PT’s activities.
• Serve as a principal scientific and operational point of contact for the Gates Foundation collaboration, accountable for delivery against agreed goals, milestones, and reporting commitments.

Scientific and Discovery Leadership

• Set the scientific direction for discovery research in…