Sr. Research Associate, Vector Production

Senior Research Associate, Vector Production

Hands‑on lab role supporting reliable AAV manufacturing and process development through execution of upstream, downstream, and QC‑support workflows, with strong emphasis on operational rigor.

Job Type: Full Time, onsite

Location:

Watertown, MA

As Senior Research Associate, Vector Production, you will be responsible for executing AAV manufacturing and process‑development lab work across upstream, downstream, and QC‑support workflows while maintaining strong documentation, sample handling, and operational discipline.

At Dyno, every role is mission‑driven. Whether in science, engineering, operations, or business, each AAViator contributes to solving some of the most complex challenges in genetic medicine.

• Execute AAV upstream, downstream, and QC‑support workflows in support of team production and development priorities
• Maintain accurate, timely documentation in lab notebooks and operational tracking systems
• Support process development experiments through careful execution, troubleshooting, and data capture
• Contribute to shared lab operations, including sample handling, inventory, and SOP updates
• Partner closely with team members to coordinate work, surface issues early, and maintain execution quality
• Work with urgency and adaptability, balancing innovation with execution.
• Collaborate cross‑functionally, leveraging Dyno’s high‑trust, high‑impact culture to drive results.

• Bachelor’s degree in biology, biochemistry, bioengineering, chemical engineering, molecular biology, or related field
• 4+ years of relevant lab experience
• Direct hands‑on experience with AAV production in a research, biotech, or process‑development setting
• Hands‑on experience with mammalian cell culture and aseptic technique
• Experience following structured lab workflows with strong attention to detail and documentation
• Ability to work effectively in a team‑based lab environment as company and project priorities evolve
• Willingness to push the boundaries of work through the use of AI
• Alignment with Dyno’s core values — We seek individuals who step up when things get tough, recalibrate when priorities shift, and thrive in a high‑expectation environment
• A proactive, problem‑solving mindset — you don’t just identify challenges; you find solutions

• Hands‑on experience with AAV downstream processing, including depth filtration, affinity chromatography, ion exchange chromatography, and UF/DF workflows
• Experience with QC support, sample tracking, or inventory management systems in a biotech or research setting
• Experience supporting process development or CMC activities for AAV or related biologic products

At Dyno Therapeutics, we are a high‑energy, high‑impact team on a mission to build high‑performance genetic technologies that transform patient lives. Our team unites world‑class molecular biologists, protein engineers, software developers, data scientists, and machine learning experts—all working together at the intersection of AI and genetic medicine.

Our culture is defined by three core values that guide everything we do:
One Mission, Proactive Responsibility, Reaching for Excellence.

These values are more than words—they drive our actions and decisions. Our greatest strength isn’t technology—it’s our work ethic. More than just technologists, we’re a team of relentlessly resourceful problem‑solvers: with an unshakable drive we generate breakthroughs at the intersection of AI and genetic medicine.

• Bring an unstoppable work ethic, stepping up when things get tough and adapting as priorities shift.
• Embrace challenges as opportunities, finding solutions where none exist and driving innovation forward.
• Operate with urgency, responsibility, and resilience, because this mission demands the best from us.

• Competitive compensation & equity—your contributions drive results, and we pay accordingly.
• Mission‑aligned, high‑trust environment—we succeed together, supporting each other through challenges.
• A career‑defining experience—work at the forefront of AI‑driven genetic medicine, tackling problems that reshape…