Associate Scientist - Bioanalysis

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.

This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and company is a biotechnology company pioneering innovative treatments for diseases that current therapies cannot effectively address. Employing groundbreaking circular RNA (circRNA) technology, along with proprietary lipid nanoparticles designed to selectively target T cells, Orna is advancing a new generation of RNA-based therapeutics. The company is focused on developing best-in-class treatments for autoimmune and oncology indications, including systemic lupus erythematosus, B-cell lymphoma, and multiple myeloma.

We are looking for a motivated Senior scientist to join the bioanalysis team and support nonclinical studies for the company’s diverse programs. Role is 100% lab-based work. The individual will actively take part in developing ligand binding assay (LBA) and PCR assays in guidance with scientists, perform sample testing and present results in team meetings. In this role you would have the opportunity to work with vibrant multi-disciplinary teams.

• Tissue processing from mice, rat and NHP invivo studies for RNA and protein extraction.
• Independently implement LBA and qPCR to measure large molecules such as protein and RNA from plasma and tissues samples.
• Perform method development and trouble shooting on LBA and qPCR-based assay with guidance.
• Provide high quality bioanalytical support with a focus on quantifications for PK, TK, PD assessment
• Deliver and present the experimental results to pre-clinical team
• Maintain detailed experimental protocols, electronic laboratory notebook

• BS with 0-4+ years of related industrial or academia experience, or MS with 0-2+ years of related industrial or academia experience.
• Major in biology, chemistry, pharmaceutical science or related fields
• Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

• Experience and knowledge in RT-QPCR, ddPCR, bDNA and Ligand binding assay
• Performing data analysis using excel and Graph Pad prism.
• Experience with Ligand binding assays on Luminex and MSD platform
• Experience in tissue sample processing is a plus

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