Sr. Research Associate, Vector Production

The Role

Senior Research Associate, Vector Production. Hands-on lab role supporting reliable AAV manufacturing and process development through execution of upstream, downstream, and QC-support workflows, with strong emphasis on operational rigor.

Job Type: Full Time, onsite

Location:

Watertown, MA

How You Will Contribute

As Senior Research Associate, Vector Production, you will be responsible for executing AAV manufacturing and process-development lab work across upstream, downstream, and QC-support workflows while maintaining strong documentation, sample handling, and operational discipline.

At Dyno, every role is mission-driven. Whether in science, engineering, operations, or business, each AAViator contributes to solving some of the most complex challenges in genetic medicine.

Responsibilities:

* Execute AAV upstream, downstream, and QC-support workflows in support of team production and development priorities

* Maintain accurate, timely documentation in lab notebooks and operational tracking systems

* Support process development experiments through careful execution, troubleshooting, and data capture

* Contribute to shared lab operations, including sample handling, inventory, and SOP updates

* Partner closely with team members to coordinate work, surface issues early, and maintain execution quality

* Work with urgency and adaptability, balancing innovation with execution.

* Collaborate cross-functionally, leveraging Dyno's high-trust, high-impact culture to drive results.

Basic qualifications

* Bachelor's degree in biology, biochemistry, bioengineering, chemical engineering, molecular biology, or related field

* 4+ years of relevant lab experience

* Direct hands-on experience with AAV production in a research, biotech, or process-development setting

* Hands-on experience with mammalian cell culture and aseptic technique

* Experience following structured lab workflows with strong attention to detail and documentation

* Ability to work effectively in a team-based lab environment as company and project priorities evolve

* Willingness to push the boundaries of work through the use of AI.

* Alignment with Dyno's core values - We seek individuals who step up when things get tough, recalibrate when priorities shift, and thrive in a high-expectation environment.

* A proactive, problem-solving mindset - you don't just identify challenges; you find solutions.

Preferred qualifications

* Hands-on experience with AAV downstream processing, including depth filtration, affinity chromatography, ion exchange chromatography, and UF/DF workflows

* Experience with QC support, sample tracking, or inventory management systems in a biotech or research setting

* Experience supporting process development or CMC activities for AAV or related biologic products

The Company

At Dyno Therapeutics, we are a high-energy, high-impact team on a mission to build high-performance genetic technologies that transform patient lives. Our team unites world-class molecular biologists, protein engineers, software developers, data scientists, and machine learning experts-all working together at the intersection of AI and genetic medicine.

Our culture is defined by three core values that guide everything we do:

* One Mission:
Everything we do is for the mission. We are a cohesive and motivated team, thinking ahead and supporting one another to overcome challenges.

* Proactive Responsibility:
We take action, inject energy into our work, and hold ourselves accountable for delivering results.

* Reaching for Excellence:
We constantly strive for excellence, fueled by curiosity, adaptability, and the courage to speak hard truths in pursuit of success.

These values are more than words-they drive our actions and decisions. Our greatest strength isn't technology-it's our work ethic. More than just technologists, we're a team of relentlessly resourceful problem-solvers: with an unshakable drive we generate breakthroughs at the intersection of AI and genetic medicine.

What You'll Give:

* Bring an unstoppable work ethic, stepping up when things get tough and adapting as priorities shift.

* Embrace challenges as opportunities, finding solutions where none exist and driving…