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Sr. Scientist I (Pre-formulation and Solid State Characterization

Job in Watertown, Middlesex County, Massachusetts, 02472, USA
Listing for: BioSpace
Full Time position
Listed on 2026-08-03
Job specializations:
  • Science
    Research Scientist, Pharmaceutical Science/ Research, Drug Discovery
Salary/Wage Range or Industry Benchmark: 146260 - 184713 USD Yearly USD 146260.00 184713.00 YEAR
Job Description & How to Apply Below
Position: Sr. Scientist I (Pre-formulation and Solid State Characterization)

The Discovery & Development team is driven by our patient-first commitment to advancing a retinal disease-focused pipeline. This function leads end-to-end R&D, from early discovery through product development, leveraging cutting-edge ophthalmology and biotechnology platforms to deliver innovative therapeutics that protect vision. By developing best-in-class, durable retinal therapies that can potentially improve outcomes and reduce treatment burden, the team plays a critical role in disrupting the treatment paradigm for serious retinal diseases.

Primary

responsibilities include, but are not limited to, the following:

Work in close partnership with Drug Substance, Analytical Development, and Formulation Development to progress API from discovery to manufacturing. With expertise in pre-formulation research and solid-state characterization, play a crucial role in advancing our discovery pipeline.

Individual Responsibilities
  • Conduct pre-formulation studies/solid-state characterization of active pharmaceutical ingredients (APIs) and ensure pre-formulation timelines are aligned with project goals.
  • Contribute to a thorough understanding of drug substance attributes, such as solubility, polymorphism, morphology, and stability and conceive formulation strategy.
  • Design and execute crystallization process with a focus on form control, particle size/morphology, yield, purity, and process understanding.
  • Identify and deploy new solid state characterization technologies as needed.
  • Prepare pre-formulation and pharmaceutical development reports and other technical documentation required for regulatory submissions.
  • Ensure that all work is conducted in accordance with applicable policies, procedures, regulatory standards and guidelines.
  • Maintain an understanding of current laws & regulations applicable to the pharmaceutical/biotechnology industry.
Primary skills and knowledge required include, but are not limited to the following:
  • Expertise in pre-formulation development of small molecules.
  • Strong lab skills with a Can-Do attitude; independently carry out pre-formulation research.
  • Highly skilled in characterization techniques such as PLM, SEM, PXRD, TGA, DSC, DVS, NMR, FTIR, Raman, and UV/Vis.
  • Skilled in independently organizing project goals and completing long-term projects on time.
  • Flexible, adaptable and collaborative style with a willingness to take on new challenges and positively respond to changes.
  • Possess high integrity and exceptional work ethic.
  • Excellent interpersonal, technical writing, and oral communication skills.
  • A team player, collaborating effectively with a broad range of internal functions.
  • Versatile, driven and curious to take on new and challenging roles and responsibilities
Level Of Education Required
  • PhD or Master in Material Sciences, Pharmaceutical Sciences or related discipline.
Number of Years of Experience in the Function and in the Industry:Sr Scientist I
  • PhD: at least 5 years of relevant experience in pharmaceutical industry
  • Master: at least 10 years of relevant experience in pharmaceutical industry
Pay range

$146,260 - $184,713 USD

Envision Your Future

With the exciting energy of a winning culture and an exhilarating pace, we are an ophthalmology company committed to
preventing blindness by developing and commercializing innovative therapeutics.

Transformational Innovation

We exist to change our patients’ lives through the power of sight. We are forward looking, embrace challenges with curiosity, and continuously seek to improve our products and ourselves by learning, problem-solving and pushing the limits of science and technology.

Unwavering Integrity

We recognize our responsibility to our patients, employees, and our community, and value the trust they put in us. We set a high ethical bar and expect responsible leadership at every level to ensure we serve those who matter most to us.

Compassionate Excellence

We believe that fun and excellence can coexist. We foster a culture where enjoying the work we do and caring for each other are as important as delivering exceptional outcomes.

Inclusive Collaboration

We strive to see through the eyes of others and work as one team. We appreciate one another’s differences and perspectives, and ensure everyone feels valued, respected and encouraged to bring their ideas forward.

Eye Point  
is proud to be an equal opportunity employer.

We believe that diversity and inclusion among our colleagues is critical to our success as a company, and we seek to recruit, develop, and retain the most talented people from a diverse candidate pool.

All applicants will be considered for employment without attention to age, race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

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