Director, Translational Sciences

Director Of Translational Sciences

Century Therapeutics is seeking a Director of Translational Sciences to serve as a senior scientific and organizational leader driving translational strategy across our early-phase clinical programs, with a primary focus on Type 1 Diabetes (T1D) and CAR-T cell therapies. This is a high-impact leadership role with broad accountability for translational science, biomarker strategy, assay development, CRO oversight, and team growth.

The Director will operate with significant independence, lead cross-functional decision-making, and serve as the internal and external face of Century's translational science capabilities. The ideal candidate brings deep scientific expertise, a track record of leading biomarker and translational programs through IND and early-phase clinical milestones, and the leadership presence to build a high-performing team, influence senior stakeholders, and represent Century in industry forums and with regulatory agencies.

The expected salary range for this role is approximately $195,000 - $218,000 depending on experience. Additional benefits offered include but are not limited to an annual performance-based bonus (prorated by start date), medical, dental, and vision insurance, matching 401K plan, and 20+ days per-year of PTO (prorated by start date).

Responsibilities include:

• Define and drive the translational science strategy across Century's early clinical pipeline, ensuring alignment with corporate objectives and clinical development priorities.
• Serve as the primary scientific owner of translational strategy across T1D and CAR-T programs, integrating biomarker objectives into clinical protocols, sample collection plans, and trial timelines.
• Lead development and execution of translational and biomarker strategies to support early-phase clinical trials, including first-in-human studies.
• Oversee and drive development, qualification, and validation of translational assays for treated patient samples.
• Define and lead Century's clinical biomarker CRO strategy, including partner selection, scope definition, assay transfer, and ongoing governance.
• Partner closely with Computational Biology and Data Science to define translational data pipelines, analysis frameworks, and visualization approaches.
• Build, lead, mentor, and develop the Translational Sciences team, establishing scientific direction, prioritization frameworks, and a high-performance culture.

Qualifications include:

• PhD or other advanced degree in Immunology, Translational Medicine, Cell & Gene Therapy, or a closely related field.
• 10+ years of relevant industry experience in clinical translational science, biomarker development, or bioanalysis, with substantial leadership experience in early clinical development.
• Demonstrated track record of driving translational strategies through IND, first-in-human, and early-phase clinical milestones.
• Experience in T1D, autoimmune disease, and/or CAR-T or other cell/gene therapy programs strongly preferred.
• Proven ability to operate at a strategic level, setting direction for a function while maintaining hands-on scientific accountability.
• Strong track record of cross-functional leadership in a matrixed organization, partnering across development, operations, regulatory, and computational teams.
• Excellent written and verbal communication skills, with the ability to translate complex translational data into clear strategic insights for diverse audiences.

Century Therapeutics Inc. is an Equal Employment Opportunity/Affirmative Action Employer - Minority/Female/Disability/Veteran. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or veteran status or any other characteristic protected by federal, state, or local law.