Post Doctoral Fellow - Rockefeller Neuroscience Institute Department of Neuroscience

Post Doctoral Fellow – Rockefeller Neuroscience Institute, Department of Neuroscience

The Department of Neuroscience at West Virginia University invites applications for a Post Doctoral Fellow to join the Hruska Laboratory. This fully funded position focuses on synaptic biology and super‑resolution imaging in Alzheimer’s disease models, supported by the National Institute on Aging.

The role leads a high‑impact project investigating the molecular architecture of synapses using advanced STED super‑resolution microscopy. You will integrate molecular biology, biochemistry, CRISPR‑based genome engineering, and advanced imaging in living and fixed neurons to uncover nanoscale organization mechanisms, link them to synaptic dysfunction, and relate findings to cognitive decline.

• Design, plan, and execute experiments using advanced imaging techniques (confocal, STED).
• Prepare and process biological samples for imaging (tissue sections, cell cultures).
• Perform image acquisition, processing, and quantitative analysis with specialized software.
• Manipulate and analyze protein or RNA expression using molecular tools to test hypotheses.
• Collaborate with lab members to interpret data and troubleshoot experiments.
• Contribute to manuscript writing, grant preparation, and presentation of results.
• Maintain detailed and organized records of experimental procedures and results.
• Present findings at national and international conferences.
• Maintain high standards of laboratory organization, rigor, reproducibility, and academic integrity.

• Ph.D. in neuroscience, molecular biology, biochemistry, or a related field.
• Experience with molecular cloning and engineering of DNA constructs.
• All qualifications must be met by the time of employment.

• Proficiency in confocal microscopy; experience with super‑resolution modalities preferred.
• Ability to work independently including designing experiments, analyzing data, and writing manuscripts.

• Culturing and/or transfecting primary cortical and/or hippocampal neurons.
• Experience with neurodegenerative disease models.

• CITI Biohazards training certificate.
• CITI Animal training certificate.
• CITI Conflict of Interest in Research certificate.

• 37.5‑hour work week.
• 13 paid holidays.
• 24 days of annual leave.
• 18 sick days per year.
• Comprehensive health insurance.
• 401(a) retirement savings with 6% employee contribution match.
• Wellness programs.

For details about this position, please contact Dr. Martin Hruska ska.edu.

West Virginia University is an Equal Opportunity Employer. We invite all qualified applicants regardless of race, color, religion, sex, national origin, age, disability, genetic information, or veteran status.