Business Operations Lead

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

The Business Operations Lead provides support in the site’s Finance, Site Operations, Operational Excellence, and Project Coordination functions. This role is responsible for financial planning and reporting, operational readiness and day‑to‑day site support, and coordination of critical cross‑functional initiatives and governance routines.

• Manages site finance operations, including budgeting/forecasting support, cost tracking, variance analysis, and routine financial reporting in partnership with Finance.
• Responsible for working directly with divisional finance and global business system leads to ensure annual spending and associated finance practices are accurate, up to date, and within compliance.
• Develops cost models for all production assets, asset purchases, and inventory management to be used in decision making, strategic analysis, and long‑range planning.
• Manages site capital requests, working with finance support groups to generate accounting codes, assign depreciation categories, and track project completion.
• Responsible for developing and reporting financial metrics to monitor plant performance and measure productivity.
• Defines and manages cost allocation methods used in product asset cost reporting, production planning, budget forecasting, and program valuations.
• Collaboratively partners with site leadership staff, Bio Pharma Manufacturing Finance Business Partner, Global Business System Lead, and Bio Pharma Manufacturing HR Business Partner to maintain financial alignment and compliance across the MA‑TC site.
• As appropriate, will join cross‑functional project teams with US/International Program Heads and finance partners to support broader PDM/Biopharma Manufacturing initiatives.
• Delivers high‑level report updates to site SLT and broader forums as required.
• Supports site leadership with annual goal setting and budgetary planning activities targeting facility sustainable margin optimization related to cost of goods and/or other sustainable margin targets.
• Supports operational excellence by establishing and improving standard work, KPIs/dashboards, governance cadences, and continuous improvement routines across business operations.
• Plan and execute logistics for site meetings and events (e.g., town halls, leadership meetings, onboarding sessions), and day‑of support.
• Establish and maintain governance forums (i.e. tier meetings) and ensure decisions, actions, and outcomes are documented and closed on time.
• Proactively executes supplementary responsibilities, special assignments, and operational tasks that emerge, ensuring alignment with the role’s scope and organizational priorities.

• B.S. or M.S. in engineering, sciences, business, supply chain, or related field.
• 5+ years of experience in business operations, finance, and project management in a regulated industry.
• Strong understanding of MPS, MRP, capacity analysis, and planning constraints in GMP manufacturing.
• Strong communication, negotiation, and stakeholder engagement skills.
• Ability to drive structure and governance in ambiguous or fast‑scaling environments.

• Advanced degree with emphasis on life sciences, purchasing, supply chain, and/or pharmaceutical business
• Experience supporting biomanufacturing operations
• Experience with Oracle and SAP financial allocation and reporting systems
• Experience in a fast‑paced company with high growth potential