System Administrator

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world.

For more information on Astellas, please visit our website at

The System Administrator supports the implementation, operation, and maintenance of digital and computerized systems within a cGMP manufacturing environment. Acting as the primary link between Operations and IT, this role manages system configuration, user access, and master data for core applications such as LIMS and E . The position ensures ongoing data integrity and 21 CFR Part 11 compliance across manufacturing and laboratory systems.

• Administer and maintain site computerized systems, including configuration, access control, and master data management.
• Serve as first-line support for user issues and coordinate system troubleshooting, change control, and periodic maintenance.
• Develop and maintain documentation including URS, configuration guides, validation protocols, SOPs, and training materials.
• Partner with IT, QA, and system vendors to manage system qualification (IQ/OQ/PQ), updates, and change management activities.
• Ensure systems operate in compliance with cGMP and data integrity standards; support internal/external audits and inspections.
• Support onboarding and training for system users and monitor compliance metrics for continuous improvement. Develop and maintain validation templates, SOPs, and training programs.

This role directly impacts digital system uptime, data integrity, and compliance readiness. The position collaborates closely with IT technical leads to ensure systems operate reliably and efficiently in a validated state.

• B.S. in biological sciences, chemistry, or related field with 5+ years (or M.S. with 3+ years) experience managing analytical or manufacturing computerized systems.
• Strong knowledge of GMP, 21 CFR Part 11, and data integrity principles.
• Experience with LIMS and/or E  system administration and validation.
• Familiarity with Windows environments, networks, and laboratory system integration.
• Excellent technical writing, communication, and troubleshooting skills.
• Demonstrated ability to work collaboratively and manage multiple priorities in a regulated setting.

• Experience in a fast‑paced, high‑growth biopharma or gene therapy environment.
• Experience with additional digital platforms (SAP, BMRAM, Labware LIMS, Tempo).
• Hands‑on experience with instrument integration or data capture workflows.

• This is an on‑site role working in a cGMP regulated manufacturing facility.
• On occasion, this role may travel to other Astellas Gene Therapies manufacturing facilities (0‑5%).

$79,800 – $125,400 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations).

• Medical, Dental and Vision Insurance
• Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year‑end shut down
• 401(k) match and annual company contribution
• Company paid life insurance
• Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
• Long Term Incentive Plan for eligible positions
• Company‑paid fleet vehicle for eligible positions
• Referral bonus program

Category Massachusetts TC

Astellas is committed to equality of opportunity in all aspects of employment.

EOE including Disability/Protected Veterans