Head of Supply Chain and Materials Management

Purpose

The Head of Supply Chain is a key member of the Manufacturing and Supply Leadership Team (MSLT), accountable for all supply chain activities supporting internal manufacturing operations at the MA‑TC site. This includes planning, ordering, goods receipt, raw material management, warehousing, logistics, trade compliance, and master data management. The role ensures uninterrupted supply for internal production, fosters continuous improvement, and partners closely with Global Procurement and Global Supply Chain to align strategies and standards.

• Lead the site Supply Chain team to support internal manufacturing and ensure material availability for production schedules.
• Implement governance and performance metrics for site‑level supply chain operations.
• Drive S&OP and site‑level planning processes to align production, inventory, and financial targets.
• Oversee ERP system functionality for accurate inventory control and material transactions.
• Manage raw material and component flow from receipt through storage and issuance to production.
• Ensure compliance with GMP, Safety, and Trade Compliance regulations across all supply chain activities.
• Coordinate with Manufacturing, Quality, Engineering, and Facilities to support production readiness.
• Develop and manage the site supply chain budget; monitor performance against targets.
• Manage vendor relationships for raw materials and critical components; ensure adherence to quality and service agreements.
• Partner with Global Procurement and Global Supply Chain to leverage global contracts and harmonize processes.
• Drive continuous improvement initiatives to optimize material flow, reduce waste, and improve OTIF performance.
• Engage, retain, and develop staff through coaching, mentoring, and career development programs.

Required:

• Bachelor’s degree in supply chain, Business, Scientific, or Engineering discipline;
  Master’s degree preferred.
• 10+ years of Supply Chain experience within biopharmaceutical manufacturing (early, late, or commercial phases).
• 8+ years of experience in GMP manufacture of biologics.
  8+ years of leadership experience.
• Proficiency with S&OP/IBP, end‑to‑end supply planning and forecasting, production scheduling, demand/supply balancing, scenario analysis, and budget performance.
• Knowledge of quality systems, cGMP, regulatory and industry standards across drug development phases.
• Understanding of regulations related to raw materials, critical components, drug substance, and drug product and how they translate into Supply Chain activities.
• Demonstrated Supply Chain expertise associated with tech transfer and scale‑up of biologics.
• Experience with negotiations, contract management, and/or procurement.
• Thorough understanding and demonstrated experience with FMEA and risk analysis.
• Computer skills: MS Office Suite; ERP (e.g., SAP or equivalent); LIMS; statistical software;
  Visio.
• Demonstrated project leadership and relationship‑building skills across internal/external partners and cross‑functional teams.
• Strong critical thinking skills and ability to make impactful decisions.
• Ability to foster a culture that embraces lessons learned and drives a proactive mindset; effective change leadership.
• Experienced at establishing clear direction, leading others, and bringing out their best.
• Regular communication with peers/team members about corporate strategy to drive awareness and capability.

Preferred:

• Familiarity with Vendor Managed Inventory (VMI) programs.
• Experience with continuous improvement methodologies (Lean, Six Sigma).
• Strong analytical and data‑driven decision‑making skills.

• This position is based in Westborough, Massachusetts and will require on‑site work to support a cGMP regulated manufacturing facility.
• This role frequently requires long periods of sitting, standing and use of hands and regular motion to include bending, stooping, and lifting up to 20 lbs.
• This position may be required to occasionally work during non‑traditional work hours and participate in an on‑call rotation for support.
• On occasion, this role may travel to other Astellas manufacturing facilities (0‑10%).
• At Astellas we recognize the…