US Medical Early Asset Director– Insights

US Medical Early Asset Director– Insights

Are you ready to turn ideas into life-changing medicines? At AstraZeneca, we are committed to addressing the unmet needs of patients worldwide through scientific innovation. In this role, you will play a crucial role in leveraging our scientific capabilities to positively impact patients' lives. Reporting directly to the Executive Director, US Medical Early Asset Team Lead, you will be part of a team focused on the development of ambitious US medical strategies for our early pipeline.

This is an opportunity to seize, design, and influence across a complex matrix system to ensure US needs are integrated into global development plans.

Manager, US Medical Early Asset – Insights will own US insight generation and decision analytics for pipeline assets from late discovery through Phase 2. You will translate ambiguity into clear, evidence-based recommendations by integrating secondary analytics, custom market research, competitive intelligence, epidemiology, and early forecasting. Partnering closely with Global/US Commercial, Medical, Clinical Development, Market Access, HEOR, and Finance, you will shape target product profiles, influence trial design, pressure-test differentiation hypotheses, and inform investment decisions at stage gates.

• Insight Strategy and
  
  Roadmap:
  
  Define the US insights learning plan across asset stages; prioritize critical unknowns and decision points, and map research/analytics to governance milestones.
• Target Product Profile and Asset Shaping:
  Pressure-test TPP elements (endpoints, attributes, device/format, administration setting, line of therapy, subsegments) via research and rapid experiments; recommend trade-offs to maximize US value.
• Primary Market Research:
  Design and lead payer/HCP/patient qualitative and quantitative studies (concept tests, message/value testing, conjoint/DTU, ethnography, discrete choice, max-diff) to refine positioning and evidence needs.
• Secondary Analytics:
  Synthesize syndicated data, claims/EMR analyses, epidemiology, treatment paradigms, and policy trends to size opportunities, refine segmentation, and anticipate adoption barriers.
• Competitive Intelligence:
  Maintain dynamic competitor profiles, trial readouts, label trajectories, and access precedents; run competitor simulations and implications for differentiation and timing.
• Early Forecasting and Scenarios:
  Build and refine early demand/adoption forecasts, market maps, and scenario trees; partner with Finance on rNPV and sensitivity analyses that reflect uncertainty and key inflection points.
• Evidence and Trial Design Input:
  Translate insight into guidance on endpoints, comparators, PROs, inclusion/exclusion, and RWE priorities that support future US adoption, labeling, and access.
• Customer and Ecosystem Mapping:
  Identify priority segments (HCPs, treatment centers, IDNs, payers, patient pathways) and define decision drivers across the care continuum to inform early brand strategy and initial field teams' structure.
• Value Proposition Development:
  Co-create early value narratives and differentiation hypotheses; test resonance and credibility with customers and iterate with Medical/HEOR and Market Access.
• Rapid Test-and-Learn:
  Stand up lightweight experiments (concept sprints, ad boards, rapid quant) to answer time-sensitive questions ahead of governance gates and external catalysts.
• Communications and Governance:
  Craft clear, concise readouts and recommendations for asset teams and governance; ensure traceability from insight to decision and document assumptions/risks.
• Vendor and Budget Management:
  Select and manage research/analytics vendors; ensure methodological rigor, compliance, and on-time, on-budget delivery.
• Compliance and Ethics:
  Conduct research and external engagements in line with US regulations and company policies for pre-approval communications and data privacy.

• Bachelor’s degree required; advanced degree preferred (MBA, MPH, MS in Market Research/Statistics, Pharm
  
  D, or related).
• 5+ years in pharma/biotech or consulting focused on market insights, new product planning, or early commercial…