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Executive Director, National Head of Sales, Rare Neurology

Job in Wilmington, New Castle County, Delaware, 19894, USA
Listing for: AstraZeneca GmbH
Full Time position
Listed on 2026-09-12
Job specializations:
  • Management
Salary/Wage Range or Industry Benchmark: 288000 - 432000 USD Yearly USD 288000.00 432000.00 YEAR
Job Description & How to Apply Below

This is a Field Based with frequent travel to Boston

The Executive Director, National Head of Sales, U.S. Rare Neurology will be responsible for all sales activities across AstraZeneca's rare neurology portfolio, including gMG, NMOSD, and emerging indications, in an increasingly competitive US market. The candidate will lead a team of Area Sales Leaders who each oversee Regional Sales Directors across the country, as well as the National Sales Operations lead and their area leads.

The Head of Sales is accountable for implementing marketing strategies, building AI-enabled subnational executional plans, and achieving annual sales goals and aggressive growth expectations in a multi-indication, multi-competitor environment. This leader will also serve as a key architect of AstraZeneca's US Rare Neurology commercial culture, patient-centric identity, and long-term franchise vision.

This position reports to the VP of the US Rare Neurology Business Unit.

You will be responsible for:

  • Portfolio Leadership
    :
    Leads Rare Neurology Sales teams in achieving sales performance targets across gMG & NMOSD indications, ensuring differentiated positioning in a crowded marketplace.

  • Strategic Execution
    :
    Develops and ensures optimal execution of the national and sub-national sales plans across the full rare neurology portfolio; manages the annual budget accordingly.

  • Team Leadership
    :
    Hires, leads, coaches, develops, motivates, and inspires the Sales Management Team (ASLs, NSO, RSDs), fostering a high-performance culture equipped to compete and win.

  • Patient Identification & Diagnostic Journey Leadership
    :
    Drives strategies to accelerate patient finding in low prevalence populations, including partnerships with diagnostic labs, genetic testing initiatives, disease awareness programs, and referral network mapping to shorten the diagnostic odyssey characteristics of rare disease patients.

  • Launch Excellence
    :
    Leads sales force readiness and execution for new indication launches, label expansions, and pipeline assets, including sizing/deployment decisions, launch playbook development, and rapid post-launch performance course-correction.

  • AI-Enabled Performance Management
    :
    Actively reviews performance metrics maximising AI-powered analytics, predictive modeling, and next-best-action tools with Area Sales Leaders to ensure timely and precise actions to address challenges and capitalize on opportunities in real time.

  • Digital and AI Innovation
    :
    Champions the adoption of artificial intelligence, machine learning, and advanced analytics tools across the sales organization to enhance HCP targeting, personalize customer engagement, optimize call planning, and accelerate decision-making.

  • Market Access & Reimbursement Partnership
    :
    Partners closely with Market Access, Trade, and Patient Services to navigate the complex reimbursement environment for high-cost rare disease therapies, including buy-and-bill, specialty pharmacy, site-of-care dynamics, payer utilization management, and prior authorization support.

  • Cross-Functional Collaboration
    :
    Collaborates closely with key internal and cross-functional partners to shape Marketing Plans and ensures the sales team completes the Rare Neurology's key strategic imperatives.

  • Capability Building
    :
    Ensures continuous development of capabilities and skills, including AI literacy, digital fluency, competitive selling acumen, anddeep neuroscience and immunology clinical expertise, in line with current and future market dynamics.

  • Customer Excellence
    :
    Oversees handling of priority accounts and ensures best-in-class customer service across academic centers, integrated delivery networks, and community accounts.

  • KOL Engagement
    :
    Creates, builds, and maintains relationships with National Key Opinion Leaders in…

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