Senior Director RWE

The Senior Director, US Evidence – Respiratory & Immunology (Real-World Evidence) is a strategic leadership role within US Medical, responsible for shaping and delivering the Real-World Evidence (RWE) strategy for the R&I portfolio. Reporting to the Executive Director, US Evidence, this leader directs a team of RWE Directors aligned to R&I, designing and executing research studies that demonstrates product value, informs medical strategy, and addresses critical evidence gaps across the portfolio.

The role partners closely with the Senior Director, US Evidence – Implementation Science (Team Lead) to ensure RWE outputs translate into practice-changing interventions through coordinated IS deployment. The Senior Director also champions the responsible, problem-led adoption of AI-enabled technologies to accelerate RWE workflows and improve methodological rigor.

The Senior Director will build and retain a diverse, inclusive, and high-performing RWE team, providing mentorship and career development for Directors. The role requires high emotional intelligence and the ability to influence without authority in a complex matrix environment, with explicit accountability for breaking silos between RWE and Implementation Science.

• Lead the development and execution of the RWE component of US Evidence Plans for the R&I therapeutic area across the product lifecycle from pre-launch to maturity.

• Partner with the Global BPM R&I Evidence team to align US evidence priorities with the global evidence strategy, ensure coherence in data sources and methodologies across regions, and co-develop assets where mutual leverage is possible.

• Champion representativeness and health equity in study design and data selection, ensuring real-world evidence reflects the patient populations we serve.

• Direct rigorous observational studies, retrospective database analyses, target trial emulations, prospective registries, and pragmatic effectiveness studies in R&I populations.

• Build, mentor, and retain a diverse, high-performing team of RWE Directors; provide career development pathways and ensure psychological safety.

• Guide the generation of economic and clinical evidence supporting value propositions for payers, ACOs, IDNs, and policy makers, with explicit alignment to US reimbursement strategies and quality measure environments.

• Partner with the Global HEPE (Health Economics & Payer Evidence) team to align US RWE outputs with HTA submissions, economic models, and value dossiers; ensure US evidence needs are reflected in global development plans.

• Partner with the Senior Director, US Evidence – Cardiovascular, Renal & Metabolism (RWE) to chart new directions for the US Evidence organization, align RWE strategy and methods across TAs, and co-shape the function's strategic agenda.

• Partner with the Senior Director, US Evidence – Implementation Science (Team Lead) to ensure RWE outputs catalyze IS-led practice change interventions; serve as the RWE point of accountability for R&I evidence plans and co-own the evidence-to-practice translation cycle.

• Cultivate and manage strategic partnerships with academic consortia, real-world data vendors, learning health systems, patient advocacy organizations, and respiratory and immunology registries and quality-measure bodies (e.g., GOLD, GINA, CHEST, ACR, NCQA, PQA).

• Partner with Field Medical leadership and Clinical Account Directors to translate RWE outputs into actionable insights for MSL and CAD engagement with health systems, IDNs, payers, and population health stakeholders.

• Oversee the facilitation of Scientific Narrative development, led by Evidence Directors, to inform the integrated messaging approach across peer-reviewed publications, congress presentations, payer dossiers,…