Associate Director HCP Marketing, ATTR

# Associate Principle Scientist – Product Discovery and Development Waltham, Massachusetts, United States of America---##

Job Description
* Do you have a passion for Science? Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you! At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.

If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.
*** Summary of the group:
** Pharmaceutical Sciences is a department within AstraZeneca’s Biopharmaceuticals R&D organization with a mission to transforming molecules into investigational medicines that address the unmet needs of future patients. Within Pharmaceutical Sciences, the Product Discovery and Development group focuses on advancing a diverse portfolio of small-molecule projects, including PROTAC- and RIPTAC-based therapeutics, across AstraZeneca’s therapeutic areas. The group’s mission is to translate innovative modalities into high-quality investigational medicines.
** Main

Duties & Responsibilities:

** We are looking for a highly motivated and authoritative individual to join the dynamic Product Discovery and Development group, supporting the small molecule projects in AstraZeneca pipeline. Main responsibilities for this role include:
* Developing analytical methods, formulations, and drug delivery systems with a focus on small molecules
* Serving as a function representative and providing pharmaceutical expertise to global project teams
* Planning and conducting experiments with minimum supervision;
Generating, evaluating, and reporting data clearly and efficiently;
Providing data interpretation and making recommendations to project teams and other partners.
* Being actively involved with novel formulation development and innovative technology evaluation.
* Working as a member of cross-functional pharmaceutical science and CMC project teams, in close collaboration with other formulators, analytical chemists, chemists and biologists at Astra Zeneca
* Presenting data at internal AstraZeneca meetings and occasionally at external meetings
** Education & Experience Requirements:
*** PhD degree in Pharmaceutical Sciences, Analytical Chemistry, Material Sciences, Biomedical Engineering, Chemical Engineering or related scientific fields with minimum 3 years, preferably 5+ years post-graduation experience in pharmaceutical and/or biotechnology environment.
* Or MS degree in Pharmaceutical Sciences, Analytical Chemistry, Material Sciences, Biomedical Engineering or related scientific fields with minimum 7 years, preferably 10+ years experience in pharmaceutical and/or biotechnology environment.
*
* Required Skills:

*** Knowledge and hands-on experience with analytical instruments for the characterization of formulation and drug products particularly in separation and chromatography (e.g., HPLC/UPLC, LC/MS, DLS, DSC, TGA, DVS, PXRD, dissolution)
* Validated ability in designcraftingptimizing formulations of poorly soluble compounds for preclinical studies including PROTACs & RIPTACs
* Knowledge and hands-on experience of enabling formulation technologies including but not limited to amorphous validated dispersion, lipid based formulation and nanoparticles
* Strong analytical, problem solving skills
* Track record of scientific excellence in terms of scientific publications, patents, and/or conference presentations
* Excellent oral and written communication skills
* Ability to effectively lead scientific/project activities
* Committed to guidelines through a process-oriented approach and growth mindset
** Desired

Skills:

*** Willingness to acquire new skills or technologies
* Work independently and collaboratively in team settings
* Modeling and simulation predictions for human oral absorption of drug products
* Broad knowledge and in-depth understanding of drug discovery and drug development
* Understanding of principals and applications of…