Sr Research Scientist - Biochemistry

Job Title:

Sr Research Scientist - Biochemistry

We are seeking a Sr Research Scientist specializing in Biochemistry to design, develop, and execute various biochemical and biophysical assays. This role involves supporting hit identification, validation, and mechanistic studies of various modalities, including inhibitors, activators, and degraders. The ideal candidate will have significant hands‑on experience in laboratory settings and expertise in enzymology, biochemical assays, and biophysics.

• Design, develop, and execute biochemical and biophysical assays to support hit identification, validation, and mechanistic studies.
• Troubleshoot assay performance issues by analyzing assay variability and optimizing protocols for robustness and reproducibility.
• Perform high-throughput screening and related assays to evaluate compound libraries, assessing affinity, specificity, and binding kinetics.
• Analyze and interpret experimental data using statistical software, presenting findings in reports and discussions.
• Support protein expression and purification workflows to generate high-quality proteins for assays.
• Operate and maintain lab instrumentation including multimode plate readers and automated liquid handlers.
• Maintain accurate and timely electronic lab notebooks and contribute to technical documentation.

• Fundamental understanding of enzymology, biochemical assays, and biophysics.
• Experience in basic biochemistry lab work, including buffer preparation, reagent generation, and assay development.
• Hands‑on experience with protein purification and characterization.
• Proficiency in data analysis and curve-fitting software such as Prism and Genedata.

• Demonstrated experience working collaboratively across various disciplines.
• Flexibility to adjust priorities to meet project goals.
• Ability to work independently or as part of a team.
• Highly organized with strong analytical, documentation, time management, and multitasking skills.
• Bachelor’s, Master’s, or Ph.D. degree in Chemistry, Biochemistry, Biophysics, Chemical Biology, or a related field.

This position is onsite and functions well in a fast-paced setting, offering the opportunity to work in a vibrant research environment.

This is a Contract position based out of Wilmington, DE.

The pay range for this position is $40.00 - $41.00/hr.

Benefits are subject to change and may be dependent on classification and length of employment. Eligible benefits for this temporary role include:

• Medical, dental, and vision
• Critical Illness
• Accident and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation, or Sick Leave)

This is a fully onsite position in Wilmington, DE.

This position is anticipated to close on Jun 18, 2026.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.