Research​/Sr. Research Investigator, Quantitative Pharmacology

Overview

A global biopharmaceutical company on a mission to solve unmet medical needs, Incyte follows science to develop proprietary therapeutics. The company has a portfolio of first‑in‑class medicines and a strong pipeline in Hematology, Oncology, Inflammation, and Autoimmunity, with headquarters in Wilmington, Delaware and operations across North America, Europe, and Asia.

We are seeking a pharmacometrician to join our Clinical and Quantitative Pharmacology organization in Translational Medicine. A Research Investigator or Senior Research Investigator will support the execution of model‑based analyses for clinical drug development, contributing to key programs under mentorship and guidance. This role will apply model‑informed drug development (MIDD) approaches to support decision‑making across phases of drug development. Candidates will be evaluated on a case‑by‑case basis to determine whether their experience aligns with the Research Investigator or Senior Research Investigator requirements.

• Conduct model‑based analyses including population pharmacokinetics (PK) and pharmacokinetics/pharmacodynamics (PK/PD), and exposure‑response modeling under the guidance of senior team members.
• Assist in identifying opportunities where modeling and simulation can advance the understanding of PK, PD, efficacy, and safety within assigned projects.
• Support the development of MIDD strategies to optimize prospective studies and inform clinical development in collaboration with partners (clinical pharmacology, biostatistics, regulatory, and clinical development teams).
• Communicate results, conclusions, and assumptions of pharmacometrics analyses to internal audiences through written reports and oral presentations.
• Stay current with scientific advancements and regulatory trends in clinical pharmacology and pharmacometrics, applying this knowledge to support drug development goals.
• Contribute to peer‑reviewed publications and internal scientific communications.

• Advanced degree in Pharmacometrics, Clinical Pharmacology, Applied Mathematics, Statistics, Engineering, or a related field.
• 0 to 2 years of related post‑doctoral experience in pharmacometrics or clinical pharmacology (industry or academic).
• Hands‑on experience with NONMEM and R for pharmacometrics analyses.
• Excellent communication skills and ability to collaborate with cross‑functional teams.
• Strong time‑management skills and ability to balance execution of multiple tasks to accomplish program goals.

Disclaimer:
The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.