Director, Clinical Imaging, Translational Sciences-Immunology

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Discovery & Pre-Clinical/Clinical Development

Translational Discovery & Development Biomarkers

Scientific/Technology

Spring House, Pennsylvania, United States of America

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

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Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

We are searching for the best talent for a Director, Clinical Imaging-Translational Science
- Immunology, to be in Spring House, PA or Cambridge, MA.

The Director, Clinical Imaging will provide strategic and scientific leadership for the development, validation, and delivery of imaging-derived endpoints to enable high-impact decision-making across the Immunology portfolio, with a primary focus on Gastrointestinal (GI) diseases. The role is US-based (Spring House, PA or Cambridge) and sits within the Translational Science organization, operating in a highly matrixed environment across Immunology Disease Area Strategy, Clinical Development, Data Sciences, Regulatory, and operational functions.

This position is intentionally scoped and graded to ensure imaging and digital capabilities are positioned as strategic assets for Immunology, driving endpoint innovation for precision medicine from early to late phase. The Director will balance innovation, platform building, and technical delivery, ensuring that advanced measurement approaches are translated into fit-for-purpose, scalable solutions that support portfolio objectives.

• Lead the GI-focused imaging measurement strategy across Immunology assets, spanning early through late-phase clinical development.
• Shape endpoint strategies integrating imaging measurements to support mechanistic understanding, proof-of-concept, and decision-enabling outcomes including regulatory.
• Partner with Disease Area Strategy and Translational Science leaders to ensure alignment with portfolio priorities and clinical development plans.
• Contribute to investment cases, governance discussions, and portfolio reviews, articulating value, readiness, and risk.

• Provide scientific oversight and accountability for imaging endpoints across early- and late-phase clinical trials.
• Ensure methods have an operationally delivery model to scale.
• Partner with clinical and operational partners across the organization, Data Sciences, and external vendors/CROs to ensure on-time, high-quality delivery.
• Support regulatory interactions related to imaging endpoints.

• Identify and advance next-generation imaging technologies with clear trajectories to GI pipeline impact from novel molecular methods through to AI-based structural endpoints.
• Lead the integration of AI-enabled analytics for imaging and digital endpoints, in close partnership with the Data Science organization.
• Co-develop AI-based solutions (e.g. automated image analysis, quantitative feature extraction, digital signal interpretation) to improve scalability, reproducibility, and decision-making in high impact areas.
• Build and sustain external collaborations with academia, technology partners, and pre-competitive consortia.
• Translate emerging methods into pragmatic clinical solutions balancing innovation with…