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Principal Enterprise Architect - AI & Agents

Job in Winston-Salem, Forsyth County, North Carolina, 27104, USA
Listing for: Jobtailor
Full Time position
Listed on 2026-07-13
Job specializations:
  • IT/Tech
    AI Engineer (Applied/Software)
Salary/Wage Range or Industry Benchmark: 118100 - 328800 USD Yearly USD 118100.00 328800.00 YEAR
Job Description & How to Apply Below

Job Summary

Within IQVIA’s AI & Technology Solutions (ATS) organization, the Architecture & Standards (A&S) group defines the IQVIA way of building technology. The Enterprise Architecture (EA) function, operating within A&S, is responsible for translating business strategy and OKRs into scalable, standards‑driven architectures that reduce technical debt, enable reuse, and transform business processes.

Job Overview

The Principal Enterprise Architect – AI & Agentic Solutions is accountable for co‑designing target‑state architectures and reference models for AI and agentic solutions, establishing enterprise guardrails (patterns, standards, and decision frameworks), and providing architectural oversight for priority initiatives.

This role maintains a portfolio‑wide perspective of business and technical capabilities, identifying cross‑cutting needs and opportunities to consolidate platforms and services across application and data domains. The Architect champions interoperability and reuse through modern architectural approaches, cloud‑native delivery, and modern data platforms deployed on Azure and AWS.

What success looks like:
  • Published and broadly adopted AI and agent reference architectures
  • Increased reuse of shared services, patterns, and templates
  • Reduced duplication of AI implementations and development efforts
  • Faster architecture reviews and approvals with fewer exceptions
  • Improved compliance readiness for regulated and high‑risk AI workloads
Key Responsibilities
  • Define, maintain, and evolve enterprise reference architectures, standards, and reusable patterns for generative AI and agentic systems.
  • Govern solution designs, including selection of appropriate technical components, ensuring delivery teams can adopt standards with minimal friction.
  • Provide architectural oversight for major AI initiatives, guiding trade‑offs across security, compliance, scalability, cost, and time‑to‑value.
  • Translate business strategies and OKRs into capability‑based roadmaps and target‑state architectures, avoiding project‑specific point solutions.
  • Drive enterprise interoperability across systems and data domains by defining integration patterns and data exchange approaches aligned with enterprise standards.
  • Partner with compliance, risk, and information security teams to ensure architectures align with global regulatory and quality expectations (e.g., GxP, GDPR, HIPAA, EU AI Act).
  • Maintain enterprise capability models and architecture artifacts using EA tools (e.g., LeanIX, Ardoq, MEGA), mapping capabilities to processes, systems, products, outcomes, and key data domains.
  • Identify opportunities to consolidate platforms and services across business units, quantifying investment implications and business benefits.
  • Guide senior stakeholders through architectural options, trade‑offs, and investment decisions using clear, business‑focused narratives and models.
  • Monitor AI, agentic, and life sciences technology trends; assess relevance and fit; and inform enterprise roadmaps, reference architectures, and innovation priorities.
  • Mentor and influence architects and senior engineers to raise overall architecture maturity and adherence to enterprise standards.
Required Qualifications
  • 10+ years of experience in enterprise or application architecture within large, complex organizations, including ownership of standards, roadmaps, and governance.
  • Proven experience designing and scaling generative AI and agentic solutions, with a strong focus on reusable patterns and operationalization.
  • Deep technical knowledge of generative AI and agentic concepts, including vector databases, RAG, tool‑use, MCP servers, HITL, evaluation frameworks, monitoring, observability, and platforms such as Lang Graph.
  • Strong cloud architecture experience on Azure and/or AWS, including modern data architectures (lakehouse, governance, cataloguing).
  • Expertise in modern integration styles (API‑first, event‑driven, microservices) and the ability to codify them into enterprise standards and reference architectures.
  • Exceptional communication, influence, and stakeholder management skills, including engagement with senior business, product, and technology leaders.
  • Experience…
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