Director, Information Technology

Overview

Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it.

At Replimune, we live by our values:

United:
We Collaborate for a Common Goal.

Audacious:
We Are Bold.

Dedicated:
We Give Our Full Commitment.

Candid:
We Are Honest With Each Other.

People are at the center of everything we do, and when it comes to our employees,
we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.

Join us, as we reshape the future.

• The Director, IT Operations and Cybersecurity is responsible for leading the company's technology infrastructure, cybersecurity strategy, and day-to-day IT operations. This role ensures employees have reliable, secure, and scalable technology solutions that support business growth, scientific innovation, and regulatory requirements.
• As a senior leader, the Director partners with executives and business stakeholders to develop and execute technology and security strategies that align with organizational priorities. The role oversees IT operations, infrastructure, cybersecurity, service delivery, risk management, and business continuity while driving operational excellence across the organization.
• The ideal candidate combines strong leadership, strategic thinking, and operational execution, with experience building high-performing teams, managing vendor relationships, and delivering technology solutions in regulated environments. This individual will play a key role in safeguarding company information, supporting critical business functions, and enabling the company's long-term growth and success.

• This position is based in our Woburn office and welcomes hybrid work! Local candidates are expected to be on-site a minimum of 2 days per week.

• Lead the overall IT operations and cybersecurity strategy for the organization.
• Ensure secure, reliable, and scalable technology services that support business objectives.
• Partner with executive leadership to align technology investments with organizational priorities and risk tolerance.
• Build, mentor, and lead high-performing IT and cybersecurity teams.
• Oversee enterprise technology infrastructure, service delivery, and operational performance.
• Manage cybersecurity programs, risk management initiatives, and regulatory compliance requirements.
• Lead incident response, business continuity, and disaster recovery planning.
• Manage technology budgets, vendor relationships, and strategic partnerships.
• Drive continuous improvement, operational efficiency, and adoption of industry best practices.
• Support business functions across research, clinical, manufacturing, quality, commercial, and corporate operations.

• 10+ years of progressive IT and cybersecurity leadership experience.
• Experience leading technology strategy, infrastructure, operations, and security programs.
• Proven success building and developing high-performing teams.
• Strong stakeholder management and executive communication skills.
• Experience working in regulated industries such as biotechnology, life sciences, healthcare, or pharmaceuticals preferred.
• Demonstrated experience operating at the senior level in complex, regulated, and research-driven environments.
• Deep understanding of enterprise and cloud security architectures, identity and access management, data protection, detection and response, and vulnerability management.
• Proven expertise in regulatory and assurance frameworks particularly in life sciences contexts.
• Pragmatic, risk-based approach to security that balances protection, usability, and scientific velocity.
• Experience supporting regulatory inspections and GxP audits.

• Bachelor's degree in Computer Science, Information Systems, Engineering, Life Sciences, Quality, or a related field.
• Certified Information Systems Security Professional certification, Certified…