Research Associate II, Analytical Development

Be a hero for our rare disease patients.

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. Our vision is to lead the future of rare disease medicine by challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life‑changing treatments.

In this role, you will execute analytical methods and manage analytical data to advance the gene therapy development for ultra‑rare diseases. This hands‑on, laboratory‑based position will maintain data visualization tools and information workflows to support Analytical Development and operate several automated/semi‑automated analytical methods. You will collaborate closely with scientists, research associates, IT, and Records Management teams to streamline data workflows.

ultra focused – Work together to fearlessly uncover new possibilities

Core Lab & Ops:
This role typically requires that the majority of the work be conducted on‑site.

• Design and execute experiments for high‑throughput genome titer testing (such as qPCR and dPCR) manually or by utilizing automation equipment (Echo liquid handler, integrated workcells, Hamilton liquid handlers).
• Generate, maintain, document and summarize analytical results in a highly organized manner.
• Assist with assay troubleshooting under supervision.
• Present results of experimentation in internal meetings and draft method development reports.
• Participate in requirement building, configuration, testing, implementation and deployment of laboratory data automation and/or data visualization solutions.
• Develop, document and deploy standard operating procedures (SOPs) that can be referenced by end users for technical assistance and training.
• Assist with other analytical lab activities such as sample handling and machinery or reagent maintenance as needed.

• Strong biological lab skills with data analysis ability in Excel, Power BI/Tableau, or a strong desire to learn these tools.
• Hands‑on experience operating molecular methods, especially PCR‑based methods.
• Proficient technical writing and communication skills, with the ability to complete relevant documentation.
• Strong motivation, excellent organizational skills, and the ability to multitask in a fast‑paced environment.
• Strong collaboration skills to work as a team member in the lab.
• Master of Science in Biology, Bioengineering, or Bioinformatics/Data Science with 0‑2 years of related experience, or a BS with 2‑4 years of related experience.

• Stand for extended periods with periodic stooping, bending, and kneeling.
• Able to lift, push, pull up to 50 lbs.
• Climb ladders and stairs of various heights.
• Work in a lab environment requiring PPE over the head, face, hands, feet, and body; may require a respirator with medical clearance.

The typical annual salary range for this full‑time position is $82,100 USD – $101,400 USD, based on location and individual experience.

• Generous vacation time and public holidays observed by the company.
• Volunteer days.
• Long‑term incentive and Employee Stock Purchase Plans.
• Employee wellbeing benefits.
• Fitness reimbursement.
• Tuition sponsorship.
• Professional development plans.
• Benefits vary by region and country.

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs.

Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, please contact Talent Acquisition at tal

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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