Principal Research Scientist , Multispecifics Engineering

Position: Principal Research Scientist I, Multispecifics Engineering
Company Description

About Abb Vie

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us at  Follow @abbvie on Linked In, ()  Facebook, Instagram () , X ()  and You Tube.

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Job Description

The Multispecifics Engineering group at Abb Vie is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting Discovery Biotherapeutics. This position will impact projects through engineering, production, and characterization of multispecific biopharmaceutical products. The ideal candidate should have extensive experience with biologics and multispecifics production platforms, analytical characterization, and a proven track record implementing multispecific engineering and production strategies to advance early- and late-stage discovery programs.

The ideal candidate will also have people and project management experience. The applicant should be an enthusiastic, creative scientist who will make tangible contributions to the pipeline.

Key responsibilities:

+ Responsible for design, engineering, and production of multispecific biologics supporting multiple therapeutic areas

+ Serve as a Multispecifics Engineering representative in cross-functional teams including the Therapeutic Area, Discovery Biotherapeutics, and Development Sciences, providing project updates, analysis, and advice; recognized expert in multispecific design and production

+ Serve as the Biologics Lead on projects to coordinate activities and transitions from hit generation through candidate nomination

+ Identify and solve technical problems independently, conceive and implement innovative research ideas

+ Ensure consistency and quality of technical reports

+ Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents

Qualifications

+ PhD or MS degree in Biochemistry, Biochemical engineering or related disciplines

+ 6+ (PhD) or 12+ (MS) years of experience in multispecific engineering or antibody engineering

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Experience with protein, biologics, fragments, or multispecifics (e.g. bispecifics, trispecifics, bispecific protein fusions) design, expression and purification

+ In-depth knowledge of the multispecific landscape, trends in design, and application across therapeutic areas including immunology, oncology, and neuroscience

+ Ability to recognize emerging areas of interest in multispecific engineering, antibody engineering, and related fields, and make connections between research ideas to advance platforms and programs

+ Excellent organizational skills and the ability to manage multiple projects simultaneously

+ Team player with the ability to operate in a fast-paced multi-disciplinary environment

+ Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong can-do attitude

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Preferred qualifications:

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Experience with sequence analysis tools (Vector NTI, Geneious, Genedata)

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Experience with mass spectrometry analysis and software (Protein Metrics)

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Experience with CRO coordination for production

+ Expert understanding of current state of protein expression/separation/analytical technologies

+ Extensive knowledge of biologic pipeline progression from exploratory through candidate nomination with program management experience preferred

+ Experience managing direct reports and providing performance evaluations and development opportunities

+ Recognized in the scientific community through a sustained record of peer-reviewed publications and patents preferred

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

+ The compensation range described below is the range of possible base pay compensation that the Company…