Senior Director, Portfolio and Technology Strategy

Responsibilities

• Lead portfolio operations across BRD ensuring alignment of development priorities, pilot capacity, resources, timelines, and execution risk across programs.
• Design and implement metric driven portfolio tracking systems to allow rapid and flexible adjustments to resource allocations according to project prioritizations.
• Collaborate with BRD clinical MFG and the BRD LT in the scheduling and prioritization of projects in the non-GMP and GMP pilot plants to deliver the portfolio.
• Serve as the primary contact to BTxPS Portfolio group, ensuring that information on new projects and technologies and changes to on-going projects is transferred into BRD in a timely manner.
• Work with ARD and PhRD portfolio groups to coordinate project initiations at PICM/PPMT and overall project progression through periodic touchpoints.
• Provide a mature and experienced perspective on portfolio tracking, project issues, and prioritization to ensure robust oversight and communication of project milestones, deliverables and issues.
• Provide strategic and technical leadership for non‑GMP pilot plants, enabling effective scale‑up, process characterization, and delivery of drug substance for pre‑clinical and clinical studies.
• Oversee pilot plant readiness, including equipment strategy, maintenance and turnaround, media and buffer support, and inventory management across sites.

• B.S. or M.S. in Chemical Engineering, Biochemical Engineering, Biology, or related field with a minimum of 12+ years of relevant experience in biopharmaceutical development or manufacturing, or Ph.D. with a minimum of 7+ years of experience.
• Proven experience leading and managing direct reports
• Extensive experience/knowledge in process development, pilot‑scale operations, and portfolio enablement for biologics and advanced therapeutic modalities.
• Demonstrated leadership of complex, multi‑disciplinary, multi‑site organizations in a matrixed environment.
• Deep understanding of GLP/GMP principles, regulatory guidance, and CMC development expectations.
• Proven ability to make strategic decisions balancing technical rigor, portfolio priorities, and execution speed.

• portfolio tracking systems
• process development
• pilot-scale operations
• project management
• resource allocation
• scale-up
• process characterization
• drug substance delivery
• inventory management
• equipment strategy

• leadership
• communication
• strategic decision-making
• collaboration
• oversight
• problem-solving
• prioritization
• organizational skills
• interpersonal skills
• flexibility

• B.S. in Chemical Engineering
• M.S. in Chemical Engineering
• Ph.D. in Chemical Engineering
• B.S. in Biochemical Engineering
• M.S. in Biochemical Engineering
• Ph.D. in Biochemical EngineeringB.S. in Biology
• M.S. in Biology
• Ph.D. in Biology