Research Associate, Research Scientist, Clinical Research

Research Associate I

Position Details: Location:
Worcester, MA;
Posted: 3/5/2026 2:02 PM;
Position Type:
Full-Time;
Salary: USD $40,000-$43,000 per year;
Requisition #: ;
Openings: 1.

POSITION SUMMARY: Under the direction of the Principal Investigator (PI) or designee, the Research Associate I provides operational support to the laboratory. The Research Associate I will perform research experiments as defined by the PI.

The Li lab is recruiting a Research Associate to perform nucleic acid chemistry to support research projects related to mRNA therapeutics and the Sponsor Research Agreement with Rhodes Therapeutics. The research projects will involve solid‑phase nucleic acid synthesis, organic synthesis, LC‑MS analysis, NMR, reverse‑phase chromatography, and other purification techniques. A bachelor's degree in chemistry is required.

Li lab works on developing platform technologies for mRNA therapeutics. We utilize a wide range of technologies including biochemistry, chemical biology, directed evolution, and high‑throughput sequencing.

• Perform laboratory experiments and may be responsible for a single research project
• Utilize all software relevant to experiment and equipment used
• Interpret data, form conclusions and decide on next steps under the direction of the PI or designee
• Maintain accurate records, may modify protocols with the approval of the PI or designee
• Review literature, publications and grants relevant to assigned projects
• Record results according to established lab, sponsor & university protocol
• Assist with performing data analysis and/or mathematical computations
• Maintain a detailed lab notebook according to lab practice
• Present findings at lab/group meetings
• Monitor laboratory supply levels and order as noted
• Prepare and label buffers, media, solutions, etc.
• Assist with and comply with all safety regulation and infection control standards
• Train on IACUC, IRB, EHS, Radiation safety protocols
• Comply with all applicable state, federal university, and sponsor policies and agreements
• Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
• Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
• Perform other duties as required

• Bachelor's degree in Biological or Natural Science, or equivalent experience
• Basic understanding of lab safety and protocols
• Knowledge of Microsoft Office products
• Ability to analyze data in a quantitative and objective manner.
• Ability to work in a team environment