Senior Scientist , Host Cell Engineering

Senior Scientist I, Host Cell Engineering

• Full-time
• Salary Min: 96500
• Salary Max: 183500
• Workday Global Grade: 17
• Compensation: USD 96,500 - USD 183,500 - yearly

We are seeking a highly‑motivated Senior Scientist to join a multidisciplinary team focused on robust production cell lines to enable Abb Vie’s clinical and commercial biologics pipeline. In this lab‑based position, the senior scientist will develop next‑generation mammalian host cell lines, leveraging advanced gene‑editing technologies and Systems Biology knowledge to engineer CHO host cells for enhanced recombinant protein productivity, improved product quality, and streamlined process efficiency.

The successful candidate will enable the biologics pipeline through production cell line development and characterization and collaborate across cross‑functional teams. Experience with cutting‑edge technologies such as CRISPR‑Cas9, Cas‑Clover, NGS, ’Omics, bioinformatics, system biology, AI, ML, HT automation, and digitalization for cell line and process optimization is highly preferred.

• Execute the genetic engineering and characterization of CHO host and production cell lines and optimize processes to improve all stages of pipeline development.
• Identify and implement advanced technologies strategically to support accelerated biological pipeline programs.
• Conduct general laboratory research proficiently and independently, adapting and troubleshooting experimental designs and equipment to meet research requirements.
• Apply creative thinking to solve complex problems and promote new technologies, while effectively communicating mission and ideas to diverse audiences.
• Author and review technical reports; present data to the group and to leadership; read literature; contribute scientific insights to project teams.
• Collaborate closely with cell line development, cell culture, analytical, purification, and bioinformatics colleagues to meet project timelines.
• Adhere to corporate standards for code of conduct, safety, materials handling, and good documentation practices.
• Manage multiple projects across therapeutic disciplines within a dynamic and fast‑paced team setting.

• Bachelor’s Degree in a scientific field with at least 10 years of related work;
  Master’s Degree with at least 8 years; or PhD with 0‑2 years of related work experience.
• Strong background in cell and molecular biology, with extensive experience in cell culture and aseptic technique.
• Experience with ’Omics, genetic engineering, flow cytometry, FACS, next‑generation sequencing, expression vector design, bioinformatics, systems biology, ML, AI, and/or modeling methods is highly desirable.
• Excellent problem‑solving skills, including critical and analytical thinking.
• Excellent communication, leadership, and project management skills, with demonstrated scientific writing and strong verbal communication.
• Demonstrated ability to independently design and execute experiments, interpret data, and identify appropriate follow‑up strategies.
• Proven track record of teamwork, adaptability, innovation, initiative, and integrity. Global mindset to thrive in a diverse culture and environment.
• Interacts well with diverse groups within function and maintains strong working relationships with internal and external collaborators.
• Ability to multitask and work within timelines in a dynamic, fast‑paced setting.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and a 401(k) plan to eligible employees. This position is eligible to participate in short‑term incentive programs.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.