Scientist , Multispecifics Engineering

Job Title

The Multispecifics Engineering group at Abb Vie is seeking a highly motivated research scientist to join a dynamic team supporting biologics drug discovery and multispecifics engineering.

Job Description

This position will impact projects through the design and production of biopharmaceutical products. The ideal candidate should have strong experience with multispecifics production and characterization. Other desirable skills include experience with antibody engineering, protein expression and purification expertise, and sequence analysis tools. The applicant should be able to analyze, document, and report data. She/he should possess excellent communication skills and be comfortable presenting in group settings.

• Maintain mammalian cell lines and optimize conditions
• Design multispecifics for production
• Prep DNA, express, and purify multispecific biologics to meet project team needs
• Help maintain DNA and protein inventory for group
• Prepare aliquots and plates for various assay and project teams and coordinate handoffs
• Generate production reports and keep lab notebooks up to date
• Present data at project team meetings and at internal meetings or conferences

• BS or MS in biology or related field with 5+ years (BS), or 2+ years (MS) of pharmaceutical and/or relevant experience
• Experience with bacterial and mammalian cell culture
• Experience with protein, biologics, fragments, and multi-specifics purification
• Experience with SEC, HIC, IEX purification utilizing AKTAs
• Experience with in vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF)
• Experience with plasmid prep, molecular cloning
• Excellent oral and written communication skills
• Excellent organization skills and the ability to execute on multiple projects simultaneously
• Team player with the ability to operate in a fast-paced multi-disciplinary environment
• Adapt to rapid changes in project priorities and timelines
• Competency with software programs, including MS Excel, Powerpoint, Word
• Preferred Qualifications:
• Experience operating automation equipment (e.g. Hamilton, Assay Map, Kingfisher) in biologics discovery processes
• Experience with setup and management of biologics and DNA inventory systems such as Freezer pro
• CHO expression experience including optimizing conditions and plasmid ratios for multispecifics
• Experience with ELISA, FACS
• Experience with mass spectrometry interpretation for complex biologics
• Experience with the software programs Geneious, Genedata, PMI, and Unicorn
• Experience with CRO coordination

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range.

This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

This job is eligible to participate in our short-term incentive programs.

Note:

No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit

US & Puerto Rico applicants seeking a reasonable accommodation,  to learn more:

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Pay Range: $75000 - 142500 USD

Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*,…