Sr Scientist II, Multispecific Antibody Engineering, Oncology

Discovery Biotherapeutics at Abb Vie is seeking a highly skilled, self‑motivated scientist to join a dynamic team supporting the design, engineering, and manufacturing of multispecifics. This position will have a significant impact by managing a group of scientists focused on the design, production, and characterization of multispecific biopharmaceutical products.

• Design, engineering, and production of multispecific biologics to support Abb Vie’s Oncology therapeutic area; apply design and engineering experience with multispecific biologics for ADC and immuno‑oncology applications.
• Manage a group of scientists within the multispecific team, focusing on the design, production, characterization of multispecific biologics, and management of multispecific inventory.
• Serve as the biologics lead on multispecific biologics projects, coordinating activities and transitions from hit generation through candidate nomination.
• Serve as a multispecific engineering representative on cross‑functional teams; recognized as an expert in multispecific design and production.
• Identify and solve technical problems independently, conceive, and implement innovative processes in research ideas.
• Present original work internally across departments and at internal and external scientific conferences; may author or co‑author peer‑reviewed scientific papers or patents.

• PhD or MS degree in Biochemistry, Biochemical Engineering, or related disciplines (culture: PhD or 12+ MS years of experience in multispecific engineering or antibody engineering).
• Experience with protein, biologics, fragments, or multispecifics (e.g., bispecifics, trispecifics, bispecific protein fusions) design, expression and purification.
• In‑depth knowledge of the multispecific landscape, trends in design, and applications across therapeutic areas including immunology, oncology, and neuroscience.
• Ability to recognize emerging areas of interest in multispecific engineering, antibody engineering, and related fields, and make connections between research ideas to advance platforms and programs.
• Excellent organizational skills and the ability to manage multiple projects simultaneously.
• Team player with the ability to operate in a fast‑paced multidisciplinary environment.
• Goal‑oriented team player with excellent verbal and written communication skills and strong can‑do attitude.

• Experience with sequence analysis tools (Vector NTI, Geneious, Genedata).
• Experience with mass spectrometry analysis and software (Protein Metrics).
• Experience with CRO coordination for production.
• Expert understanding of current state of protein expression, separation, and analytical technologies.
• Extensive knowledge of biologic pipeline progression from exploratory through candidate nomination with program management experience preferred.
• Experience managing direct reports and providing performance evaluations and development opportunities.
• Recognized in the scientific community through a sustained record of peer‑reviewed publications and patents preferred.

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range;
  
  this range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees.
• This job is eligible to participate in our long‑term incentive programs.

Note:

No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employer remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

U.S. & Puerto Rico only – applicants to this position must be located in the United States or Puerto Rico.