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Head of Engineering

Job in Chicago, Cook County, Illinois, 60290, USA
Listing for: BiomeSense
Full Time position
Listed on 2026-07-05
Job specializations:
  • Engineering
    Test Engineer, Systems Engineer, Electronics Engineer, Product Engineer
Salary/Wage Range or Industry Benchmark: 125000 - 200000 USD Yearly USD 125000.00 200000.00 YEAR
Job Description & How to Apply Below

Head of Engineering

Compensation: $125K– $200K salary, up to 1.0% equity stock options

Full benefits, including health coverage, PTO & parental leave

About Biome Sense

Biome Sense is a life sciences startup applying gut microbiome technologies (Gut Lab, Meta Biome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by Lab Corp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.

Role Summary

Own the full hardware (HW) lifecycle for Gut Lab, from architecture & subsystem integration through manufacturing, validation & deployment for a complex electromechanical device & BOM. Act as final technical authority for Gut Lab system performance, fleet stability & next generation Gut Labs (Gen3) production, combining hands‑on engineering depth with strategic judgment to ensure current systems perform reliably in the field & Gen3 scales into manufacturing.

Key Responsibilities
  • System Ownership & Development:
    Own Gut Lab architecture (electromechanical & fluidic); lead design, testing & refinement via CAD, prototyping & manufacturing
  • Validation & Deployment Readiness:
    Own validation, stage gates, documentation & traceability across revisions, firmware & field performance. Lead troubleshooting, diagnostics & closed‑loop fixes to eliminate systemic failure modes
  • End-to-End Execution:
    Set & execute high standards for all aspects of HW development: procurement, transfer, sustaining engineering & operations
  • Manufacturing Scale‑Up:
    Drive DFM, design freeze, pilot builds, supplier alignment, cost targets & manufacturing strategy + execution for Gen3
  • Team Leadership:
    Mentor & lead a HW team; align resources, timelines & execution to production milestones
  • Strategic Problem Solving:
    Address any and all procurement challenges while identifying cost‑effective solutions
  • Cross‑Functional

    Collaboration:

    Partner with other leaders to align hardware development with broader company strategy & goals
Qualifications
  • 8+ years’ experience in hardware engineering for complex electromechanical systems
  • Deep proficiency in CAD, tolerances, prototyping & manufacturing
  • Product lifecycle ownership (concept through transfer & scale‑up)
  • Proven ability to build & manage technical teams
  • Systems‑level troubleshooting expertise across mechanical, fluidic & electronic
  • Structured, decisive & execution‑oriented with high accountability
  • A strategic thinker who thrives under pressure in fast‑paced environments
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