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Data Architect, Clinical

Job in Chicago, Cook County, Illinois, 60290, USA
Listing for: Prolaio
Full Time position
Listed on 2026-07-07
Job specializations:
  • IT/Tech
    Data Engineering
Salary/Wage Range or Industry Benchmark: 133200 - 162800 USD Yearly USD 133200.00 162800.00 YEAR
Job Description & How to Apply Below

Who Are We?

Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients, care teams, and researchers on a secure, technology-enabled platform that drives clinical innovation and offers a path towards better patient outcomes.

This is precision cardiology, and we know it’s within reach.

What Will You Do? The Overview

The Data Architect will shape the backbone of Prolaio’s healthcare data ecosystem, defining and scaling the architectures that power clinical intelligence products, real‑world data pipelines, analytics, data science, clinical operations, quality, and other enterprise use cases in a regulated environment. In this role, you turn complex clinical and operational data into interoperable, trustworthy, and scalable platforms that enable Prolaio to transform continuous, predictive, and shareable heart data into faster therapeutic discovery and better cardiovascular outcomes.

This role is ideal for a self‑starter with deep healthcare data experience who wants to architect modern platforms across structured, semi‑structured, and unstructured data, embedding lifecycle management, standardization, lineage, provenance, compliance, and AI enablement into the foundation of Prolaio’s data ecosystem.

The Specifics
  • Define the target-state data architecture and roadmap for Prolaio’s regulated healthcare data platform in support of product, analytics, data science, data services, clinical operations, and quality use cases.
  • Architect scalable, secure, and interoperable data platforms that support structured, semi-structured, and unstructured data across clinical, operational, device, and patient-generated sources relevant to Prolaio’s cardiovascular and research mission.
  • Lead architecture decisions for storage, compute, orchestration, metadata, APIs, and integration patterns across cloud-native environments and modern data platforms.
  • Establish architecture standards and reference patterns that support reliability, performance, extensibility, and validated operation in regulated settings.
  • Design and govern conceptual, logical, and physical data models for clinical trials, cardiovascular and physiological data, real-world data, claims, medication, socio-economic, behavioral, and related healthcare datasets.
  • Apply healthcare terminologies, ontologies, and common data models where appropriate, including standards such as HL7, FHIR, ICD, SNOMED CT, LOINC, RxNorm, OMOP, and CDISC.
  • Lead efforts to standardize and normalize disparate data sources into governed, reusable, analysis-ready datasets suitable for regulated workflows, clinical research, and product development.
  • Architect end-to-end data flows and reusable pipelines for ingestion, validation, transformation, enrichment, publishing, retention, archival, and decommissioning across batch, streaming, and hybrid workloads.
  • Define and implement data lifecycle management practices that support retention, access control, traceability, reproducibility, lineage, provenance, and auditability in regulated healthcare environments.
  • Design data architectures that enable AI, analytics, and machine learning use cases by supporting feature generation, retrieval workflows, governed access, and production deployment needs.
Why Prolaio?
  • Impactful Work: You will join in the fight against heart failure (HF) and hypertrophic cardiomyopathy (HCM) with the goal of extending and saving the lives of our patients while also being at the forefront of changing the healthcare industry through technology.
  • Innovative Environment: You will be part of an organization doing something that’s never been done before.
  • Professional Growth: You will join a growing team and have a substantial impact on our daily and future operations with the opportunity to continuously learn and grow.
  • Collaborative Team: You will be part of a team of collaborative, curious, and committed individuals focused on the collective good, inclusiveness, scientific excellence, and advancing digital health for cardiology.
Who You Are?
  • Bachelor’s degree in computer science, Data…
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