Senior Scientist , Drug Product Design and Development

Company Description

About Abb Vie

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us at  Follow @abbvie on Linked In, Facebook, Instagram, X and You Tube.

The Drug Product Design and Development (DPDD) group within the Synthetic Molecule CMC organization at Abb Vie is responsible for the design and development of drug products that enable the delivery of Abb Vie’s candidate synthetic molecules in dosage forms to support various stages of clinical evaluation, from proof of concept to pivotal studies and life cycle innovation. DPDD collaborates with cross functional teams to devise an integrated and phase appropriate drug product development strategy, design and execute studies to develop bioavailable, stable and manufacturable drug products, and ensure timely delivery of clinical supplies.

DPDD is also accountable for optimizing formulation and manufacturing processes to develop commercializable drug products for Phase 3 clinical studies, meeting the needs of the patients we serve and ensuring consistent production of high‑quality drug products.

Abb Vie's DPDD organization is seeking a highly motivated and talented leader with experience and expertise in developing drug products for a Senior Scientist I position to join our team based in North Chicago, IL. The candidate will work with cross‑functional teams to develop drug delivery and formulation strategies, lead the design, characterization and understanding of formulations/processes, as well as advance biopharmaceutical characterizations of clinical formulations.

In this role, the candidate will play a crucial role as a project lead within dynamic, engaging, and cross‑functional teams with the ability to apply expertise and leadership skills to advise teams, solve complex problems and drive innovation. The candidate is also expected to foster productive collaborations and demonstrate effective communication within scientific teams and senior CMC management.

• Lead the formulation design for small molecule development candidates within the Abb Vie pipeline.
• Interface with drug product development teams to ensure that biopharmaceutical and physicochemical considerations are incorporated into formulation design.
• Advance scientific expertise within function. Proactively demonstrate leadership by advising and sharing knowledge and expert opinions with subordinates, peers, and senior management.
• Ensure development of technologies and scientific innovation that improve the capability to formulate small molecules within the Abb Vie pipeline.
• Collaborate with other functions within Abb Vie to align a broad range of strategies that directly support drug discovery and development programs.
• Ensure compliance with Abb Vie safety, quality and regulatory policies and government regulations.

• MS (8-10 yr. experience) or PhD (0-3 yr. experience) in Pharmaceutics, Physical Pharmacy, Biopharmaceutical Sciences, Biomedical Engineering, Chemical Engineering, or Material Sciences.
• Strong theoretical background and practical background in formulation design and pharmaceutical technologies.
• Fundamental understanding of physicochemical and biopharmaceutical properties as related to formulation design.
• Technical awareness in various aspects of drug development, adherence to rigorous scientific method, and commitment to the scientific process.
• Scientific problem solving, experimental design and troubleshooting skills.
• Excellent oral and written communication skills.
• Demonstrated ability to work collaboratively in a cross‑functional team setting.

• Strong knowledge of long‑acting injectable (LAI) technologies.
• Fundamental understanding of physicochemical properties related to LAI formulation design.
• Experience in developing LAI formulations.
• Profic…