Research Lab Manager

Position: Research Lab Manager 1
Department: MED-Neurology

Salary/Grade: EXS/6

Target hiring range for this position will be between $56,782-$70,975 per year. Offered salary will be determined by the applicant's education, experience, knowledge, skills and abilities, as well as internal equity and alignment with market data.

The Carvill Lab in the Department of Neurology is seeking a new Lab Manager to join our team. Our research focuses on the genetic and epigenetic basis of epilepsy; we use numerous genomic technologies as well as iPSCs to study pathogenic mechanisms towards discovering new precision therapies. We are seeking a Lab Manager to work on multiple NIH and Foundation-funded research projects, as well as to oversee the general day to day running of the lab.

Learn more about our work and the team here: (Use the "Apply for this Job" box below)./

Job Summary:

Manages daily operations of a research lab. Monitors lab performance, analyzes and reviews results, and supervises development and implementation of new protocols. Assigns work and supervises lab personnel and reviews technical operations ensuring that all processes, protocols and procedures are quality controlled and functioning up to standards. Develops implements and administers budgets, grant and administrative procedures. Co-authors scientific papers for presentation and publication and coordinates writing, submission and administration of grants.

Specific Responsibilities:

* Manages technical operations of a lab involved in scientific research activities.

* In consultation with Principle Investigator (PI) organizes and plans experiments ensuring those project objectives are attained.

* Oversees and guides lab staff in review of results and recommendation of changes to protocols to improve validity and accuracy.

* Conducts more complex experiments and analysis.

* Using an advanced level of skill, completes the following activities

Molecular Biology:

* DNA, RNA, Protein isolation, purification and expression

* Southern, Northern, Western blotting

* PCR, RT-PCR

* Plasmid preparation

* Cloning, mapping and sequencing of DNA

* Recombinant virus production and purification

Cellular Biology:

* Cell culture, cell isolation

* Functional studies

* Transfection

Histology:

* Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining

* Immunohistochemistry

* Microscopy

Immunology:

* Flow cytometry

* ELISA, Elispot assay

* Cytokine assay

* Antibody production and purification

Animal:

* Husbandry

* Breeding and screening transgenic mice

* Dissections

* Blood collection

* Surgical procedures

* Database management of colony

Administration

* Oversees and manages collection, maintenance, analysis and evaluation of data that will be used in grant submissions, presentations and publications.

* Ensures that information is entered correctly into databases.

* Assists PI in reviewing, analyzing, interpreting, summarizing, formatting, editing, and preparing tables, charts, graphs, progress and final reports, etc.

* Coordinates between sponsoring agencies, collaboration organizations and/or other research and/or educational institutions.

* Ensures research regulations are adhered to, IRB and ACUC approvals in place, material transfer agreements properly executed, and that radiation and lab safety requirements are up to date and implemented.

Finance

* Manages lab budget and inventory including purchasing of supplies and services ensuring that they are necessary, reasonable and project related.

* Orders and maintains inventory of lab supplies, chemicals, equipment and instrumentation and may distribute intra-departmental charges.

* Negotiates with vendors, obtain quotes and arrange for demos of large equipment.

Supervision

* Trains, directs, assigns duties to & supervises lab EEs, students, residents &/or fellows.

* Provides instruction to lab users on technically complex procedures, equipment & instruments.

* Typically manages a lab budget of $1,000,000-$3,000,000; 1,000 - 3,000 nasf of space & supervises 5-15 lab members.

Miscellaneous

Performs other duties as assigned.

Minimum Qualifications:

* Successful completion of a full 4-year course of study in an accredited college or university leading to a…