Senior Director, Evidence Generation

Responsibilities

• Develop and execute integrated HEOR and evidence generation strategies across the product lifecycle (portfolio planning and lifecycle management).
• Define the vision, structure, and capabilities of the Evidence Generation team (future state) with Medical Affairs leadership.
• Identify evidence gaps; prioritize studies to support payer/provider/institution/patient decision‑making.
• Provide HEOR input to clinical development (endpoint selection and evidence planning).
• Lead economic modeling: budget impact analyses, cost‑effectiveness studies, and value dossiers.
• Oversee comparative effectiveness and burden‑of‑illness evidence generation.
• Guide development of patient‑reported outcomes (PRO) and health‑related quality‑of‑life research.
• Ensure methodological rigour for all real‑world evidence (RWE) initiatives; align projects with medical and brand strategy.
• Evaluate/acquire novel data sources; oversee retrospective database analyses, pragmatic trials, and outcomes research with medical/scientific leads and external experts.
• Build relationships with external researchers and evidence‑generation partners.
• Manage strategic/internal‑external communications for successful completion and data disclosure; provide executive‑level engagement.
• Oversee external vendors/partnerships; collaborate with Publications/Medical Communications to publish research.

• PhD/DrPH/ScD/PharmD/MD or equivalent in Health Economics, Outcomes Research, Epidemiology, Public Health, Health Services Research, Biostatistics, Pharmacy, Medicine, or related field.
• Demonstrated expertise in health economics/pharmacoepidemiology/biostatistics/RWE.
• 12+ years in HEOR/outcomes research/epidemiology/market access/evidence generation (pharma/biotech/consulting/healthcare).
• Experience supporting payer engagement and reimbursement strategy.
• Track record of peer‑reviewed publications and major congress presentations.

• Health economics modelling and value assessment; RWE strategy; comparative effectiveness; PRO/QoL; epidemiology/observational design; market access/reimbursement; HTA; evidence synthesis/SRLs; data analytics/healthcare databases; scientific communications.

Periodic evening/weekend work; periodic overnight travel; vehicle and air travel possible; hybrid in Chicago requiring at least 3 days/week on‑site.

Anticipated base salary range: $252,000–$337,000.

If you need a reasonable accommodation during the application process, email  with the job requisition number.